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Jinhyuk Bhin Professor Biomedical Systems Informatics

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Detail Major

Bioinformatics, Oncogenomics, Proteogenomics

  • Career
  • Research

Career

Academic records

  • 2010.3 - 2016.2 Ph.D. POSTECH

Education and research career

  • 2023.3 - Present Assistant Professor, Yonsei University College of Medicine
  • 2017.1 - 2022.12 Postdoc, Netherlands Cancer Institute
  • 2016.3 - 2016.12 Postdoc, Institute for Basic Science, DGIST

Academic career

  • Committee of Scientific Affairs, Korea Cancer Association
  • Committee of Education, Korea Society for Biochemistry and Molecular Biology
  • Committee of Public Relation, Korea Society of Bioinformatics

Research Interests

  • Identifying novel clinically actionable oncogenes using cancer genomic profiles
  • Uncoverying resistance principles against anti-cancer therapeutics using single cell multi-omics data
  • Developing analytical tools for proteogenomic analyses

Major achievements

  • MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer, Journal of Experimental Medicine (2023)
  • Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors, Cell Reports (2023)
  • Truncated FGFR2 is a clinically actionable oncogene in multiple cancers, Nature, 2022
  • Proteogenomic characterization of human early-onset gastric cancer, Cancer Cell, 2019
  • Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10-p63 axis in epithelial homeostasis, Proc Natl Acad Sci U S A, 2017
  • Pontin functions as an essential coactivator for Oct4-dependent lincRNA expression in mouse embryonic stem cells, Nature Communications, 2015
  • [full publications] https://scholar.google.com/citations?use=2TDl2b8AAAAJ&hl=en&oi=ao