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소속

  • 정신과학교실

직위

  • 교수

연구실 위치

  • 연세대학교 의과대학 5층

전화/팩스

  • 02-2228-1633 /

학력사항

  • 연세대학교 의과대학 학사 (1994)
    연세대학교 대학원 의학석사 (1999)
    연세대학교 대학원 의학박사 (2003)

교육 및 연구 경력

  • 1994-1995 연세대학교 의과대학 세브란스병원 인턴
    1995-1999 연세대학교 의과대학 세브란스병원 정신과 전공의
    1999-2000 연세대학교 의과대학 세브란스병원 소아정신과 강사
    2000-2001 성균관의대 강북삼성병원 소아정신과 전임의
    2001-2003 연세대학교 의과대학 강남세브란스병원 소아정신과 연구강사
    2003-2009 관동의대 명지병원 정신과학교실 조교수 및 부교수
    2009-2010 미국 펜실베이니아대 의과대학 필라델피아 아동병원 발달뇌영상 연구소 방문교수
    2009-2010 뉴욕대학교 의과대학 Child Study Center, Institute for Pediatric Neuroscience 연수
    2010-2016 연세대학교 의과대학 세브란스병원 정신과학교실 부교수
    2017-現 연세대학교 의과대학 세브란스병원 정신과학교실 교수

기타 학술 관련 경력

  • [학회활동 및 소속학회]
    한국자폐학회 이사
    대한소아청소년정신의학회 총무이사 및 국제이사 역임
    대한신경정신의학회 정회원
    대한정신약물학회 비상임이사,
    대한소아청소년정신의학회 학술위원회 간사 역임
    대한우울조울병학회 비상임 이사
    Member of the International Society for Neuroimaging in Psychiatry (ISNIP)
    Member of Collegium Internationale Neuropsychopharmacologicum (CINP)
    Member of ADHD international Molecular Genetic Network
    Psychiatry Investigation, Advisory Board Member
    Corresponding Member of American Academy of Child and Adolescent Psychiatry(AACAP)

    [Professional Journal Reviewer Activity]
    Ad Hoc Reviewer, NeuroImage
    Ad Hoc Reviewer, Archives of General Psychiatry
    Ad Hoc Reviewer, Journal of Child Psychology and Psychiatry
    Reviewer, Yonsei Medical Journal
    Reviewer, Korean Journal of Medical Science

    [수상경력]
    2003.2 강사 학술상 (연세의대 강남세브란스병원)
    2005.3 최우수 논문상 (대한정신약물학회)
    2005.10 GSK 젊은 의학자상 (대한신경정신의학회)
    2006.9 Donald J. Cohen Fellow Award (세계소아청소년정신의학회)
    2008.2 교수 학술상 (관동대학교 명지병원)
    2008.1 세계 100대 의학자 (IBC: 국제인명센터,영국)
    2010.4 중앙정신의학 논문상 (대한신경정신의학회)
    2012.5 최우수 논문상 (대한소아청소년정신의학회)
    2013.11 소천 학술상 (대한소아청소년정신의학회)
    2017.11 노경선 저작상 (대한소아청소년정신의학회)

연구,관심분야

  • 1) 자폐스펙트럼 장애의 연구 (유병률 연구, Functional MRI, Diffusion Tensor Imaging을 이용한 neural connectivity research, 역분화 줄기세포 연구)
    2) ADHD 분자유전학적, 약물유전학적 연구

강의분야

  • 소아정신의학,ADHD,자폐스펙트럼장애,행동과학

논문

  • Dopamine transporter density in the basal ganglia assessed with [123I]IPT SPET in children with attentionassessed with [123I]IPT SPET in children with attention deficit hyperactivity disorder
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 30/2 :306-311,2003
  • 뚜렛 장애 아동에서 Risperidone 치료 전후 [123I]IPT SPECT로 측정한 기저 신경절 도파민 운반체 밀도
    대한핵의학회지(Korean Journal Of Nuclear Medicine) 38/1 :41-51,2004
  • Dopamine transporter density of the basal ganglia assessed with [123i]IPT SPECT in drug-nave children with Tourette's disorder.
    PSYCHIATRY RESEARCH-NEUROIMAGING 130/1 :85-95,2004
  • The homozygosity for 10-repeat allele at dopamine transporter gene and dopamine transporter density in Korean children with attention deficit hyperactivity disorder: Relating to treatment response to methylphenidate
    EUROPEAN NEUROPSYCHOPHARMACOLOGY 15/1 :95-101,2005
  • Family-based association study of DAT1 and DRD4 polymorphism in Korean children with ADHD
    NEUROSCIENCE LETTERS 390/3 :176-181,2005
  • Family-based association study of the serotonin transporter gene polymorphisms in Korean ADHD trios
    AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 139B/ :14-18,2005
  • Dopamine transporter density in the basal ganglia in obsessive-compulsive disorder, measured with [123I]IPT SPECT before and after Treatment with Serotonin Reuptake Inhibitors
    NEUROPSYCHOBIOLOGY 55/ :156-162,2007
  • Association of 4-repeat allele of the dopamine D4 receptor gene exon III polymorphism and response to methylphenidate treatment in Korean ADHD children
    NEUROPSYCHOPHARMACOLOGY 32/6 :1377-1383,2007
  • Association study of dopamine D2, D4 receptor gene, GABAA receptor beta subunit gene, serotonin transporter gene polymorphism with children of alcoholics in Korea: A preliminary study
    Alcohol 42/ :77-81,2008
  • Association of the catechol-O-methyltransferase polymorphism with methylphenidate response in a classroom setting in children with attention-deficit hyperactivity disorder
    International Clinical Psychopharmacology 23/5 :291-298,2008
  • The Impact of Individual and Methodological Factors in the Variability of Response to Methylphenidate in ADHD Pharmacogenetic Studies from Four Different Continents
    American Journal Of Medical Genetics Part B-Neuropsychiatric Genetics 147(B)/8 :1419-1424,2008
  • Association Between Homozygosity of a G Allele of the Alpha-2a-Adrenergic Receptor Gene and Methylphenidate Response in Korean Children and Adolescents with Attention-Deficit/Hyperactivity Disorder
    Biological Psychiatry 65/7 :564-570,2009
  • Association between Dopamine D4 Receptor Gene Polymorphism and Scores on a Continuous Performance Test in Korean Children with Attention Deficit Hyperactivity Disorder
    Psychiatry Investigation 6/ :216-221,2009
  • Norepinephrine transporter gene (SLC6A2) is involved with methylphenidate response in Korean children with attention deficit hyperactivity disorder
    INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY 26/2 :107-113,2011
  • The 1287 G/A polymorphism of the Norepinephrine Transporter gene (NET) is involved in Commission Errors in Korean children with Attention Deficit Hyperactivity Disorder
    BEHAVIORAL AND BRAIN FUNCTIONS 7/12 :-,2011
  • Prevalence of autism spectrum disorders in a total population sample
    AMERICAN JOURNAL OF PSYCHIATRY 168/9 :904-912,2011
  • Involvement of the anterior thalamic radiation in boys with high functioning autism spectrum disorders: A Diffusion Tensor Imaging study
    BRAIN RESEARCH 1417/0 :77-86,2011
  • Titrating Optimal Dose of Osmotic-Controlled Release Oral Delivery (OROS)-Methylphenidate and Its Efficacy and Safety in Korean Children with ADHD: A Multisite Open Labeled Study
    PSYCHIATRY INVESTIGATION 9/3 :257-262,2012
  • Emotion-on-a-chip (EOC): Evolution of biochip technology to measure human emotion using body fluids
    MEDICAL HYPOTHESES 79/6 :827-832,2012
  • Comparison of Aripiprazole and Other Atypical Antipsychotics for Pediatric Bipolar Disorder: A Retrospective Chart Review of Efficacy and Tolerability
    Clinical Psychopharmacology and Neuroscience 11/2 :72-79,2013
  • A Comparison of DSM-IV Pervasive Developmental Disorder and DSM-5 Autism Spectrum Disorder Prevalence in an Epidemiologic Sample
    JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY 53/5 :500-508,2014
  • A Comparison of Receptive-Expressive Language Profiles between Toddlers with Autism Spectrum Disorder and Developmental Language Delay
    YONSEI MEDICAL JOURNAL 55/6 :1721-1728,2014
  • Psychological Problems and Clinical Outcomes of Children with Psychogenic Non-Epileptic Seizures
    YONSEI MEDICAL JOURNAL 55/6 :1556-1561,2014
  • Advanced Pharmacotherapy Evidenced by Pathogenesis of Autism Spectrum Disorder
    CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE 12/1 :19-30,2014
  • Screening for depression and anxiety disorder in children with headache
    Korean Journal of Pediatrics 58/2 :64-68,2015
  • Abnormal Activation of the Social Brain Network in Children with Autism Spectrum Disorder: An fMRI Study
    PSYCHIATRY INVESTIGATION 12/1 :37-45,2015
  • The Relationship Between Symptomatic and Functional Changes of Korean Children and Adolescents With Attention-Deficit/Hyperactivity Disorder Treated With Osmotic-Controlled Release Oral Delivery System-Methylphenidate
    CLINICAL NEUROPHARMACOLOGY 38/1 :30-35,2015
  • A New Approach to Investigate the Association between Brain Functional Connectivity and Disease Characteristics of Attention-Deficit/Hyperactivity Disorder: Topological Neuroimaging Data Analysis
    PLOS ONE 10/9 :e0137296-,2015
  • Idiom Comprehension Deficits in High-Functioning Autism Spectrum Disorder Using a Korean Autism Social Language Task
    YONSEI MEDICAL JOURNAL 56/6 :1613-1618,2015
  • Abnormal Brain Activity in Social Reward Learning in Children with Autism Spectrum Disorder: An fMRI Study
    YONSEI MEDICAL JOURNAL 56/3 :705-711,2015
  • Association Between 5-HTTLPR Polymorphism and Tics after Treatment with Methylphenidate in Korean Children with Attention-Deficit/Hyperactivity Disorder.
    JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY 25/8 :633-640,2015
  • Characteristics of Brains in Autism Spectrum Disorder: Structure, Function and Connectivity across the Lifespan
    Experimental Neurobiology 24/4 :273-284,2015
  • The Tourette International Collaborative Genetics (TIC Genetics) study, finding the genes causing Tourette syndrome: objectives and methods
    EUROPEAN CHILD & ADOLESCENT PSYCHIATRY 24/2 :141-151,2015
  • Abnormalities of Inter- and Intra-Hemispheric Functional Connectivity in Autism Spectrum Disorders: A Study Using the Autism Brain Imaging Data Exchange Database
    FRONTIERS IN NEUROSCIENCE 10/191 :1-11,2016
  • Neural responses to affective and cognitive theory of mind in children and adolescents with autism spectrum disorder
    NEUROSCIENCE LETTERS 621/ :117-125,2016
  • The effect of epilepsy on autistic symptom severity assessed by the social responsiveness scale in children with autism spectrum disorder.
    BEHAVIORAL AND BRAIN FUNCTIONS 12/20 :1-9,2016
  • The Social Responsiveness Scale in Relation to DSM IV and DSM5 ASD in Korean Children
    AUTISM RESEARCH 9/9 :970-980,2016
  • Adjunctive alpha-lipoic acid reduces weight gain compared with placebo at 12 weeks in schizophrenic patients treated with atypical antipsychotics: a double-blind randomized placebo-controlled study
    INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY 31/5 :265-274,2016
  • Effects of high-frequency repetitive transcranial magnetic stimulation (rTMS) on spontaneously hypertensive rats, an animal model of attention-deficit/hyperactivity disorder
    INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE 53/ :83-89,2016
  • Pre- and perinatal complications in relation to Tourette syndrome and co-occurring obsessive-compulsive disorder and attention-deficit/hyperactivity disorder
    JOURNAL OF PSYCHIATRIC RESEARCH 82/ :126-135,2016
  • Cross-Cultural Aspect of Behavior Assessment System for Children-2, Parent Rating Scale-Child: Standardization in Korean Children.
    YONSEI MEDICAL JOURNAL 58/2 :439-448,2017
  • Factors Associated with Emotional Distress in Children and Adolescents during Early Treatment for Cancer.
    YONSEI MEDICAL JOURNAL 58/4 :816-822,2017
  • The Relationship between the SNAP-25 Polymorphism and Omission Errors in Korean Children with Attention Deficit Hyperactivity Disorder
    CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE 15/3 :222-228,2017

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