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소속

  • 정신과학교실

직위

  • 교수

연구실 위치

  • 세브란스병원

전화/팩스

  • 02-2228-1585 /

학력사항

  • 1984.-1990. 연세대학교 의과대학 의학과 졸업
    1995.-1997. 연세대학교 대학원 의학과 정신과학전공 의학석사
    1997.-2001. 연세대학교 대학원 의학과 정신과학전공 의학박사

교육 및 연구 경력

  • 1998. 연세대학교 의과대학 세브란스병원 정신과 전문의 취득
    2000-현재. 연세대학교 의과대학 정신과학교실 전임강사, 조교수, 부교수, 교수
    2006-현재. 연세대학교 의과대학 의학행동과학연구소 정동 및 신경과학 섹션 책임교수
    2004-2009. Institute of Psychiatry, Psychology & Neuroscience, King's College, London, United Kingdom의 Visiting Senior Lecturer

기타 학술 관련 경력

  • <학회>
    - 2004. 국제 조현병 학회 (Schizophrenia International Research Society)의 창립 회원
    - 2002-현재. 대한조현병학회 학술이사, 국제이사, 기획이사 등 상임이사
    <논문심사위원>
    - Schizophrenia Bulletin, Schizophrenia Research, Early Intervention in Psychiatry,
    Psychiatry Research, Comprehensive Psychiatry, Psychiatry Investigation,
    신경정신의학, 대한조현병학회지등 연구 논문 잡지의 심사위원
    <기타>
    - 2008년 생물학연구정보센터(BRIC)에서 “한국을 빛내는 사람들”에 선정

연구,관심분야

  • <주요관심분야>
    - 임상: 조현병, 정신증 고위험군(고립, 방황, 혼란, 착각 및 낯선 소리)
    - 연구: 조현병의 자기경험장애, 조현병 및 정신증 고위험군의 자기경험, 정서 및 사회 인지 손상 기전 규명 및 치료프로그램 개발

강의분야

  • 정신병리학
    조현병
    신경과학
    정신과적 통계

논문

  • Positive and negative symptoms and regional cerebral perfusion in antipsychotic-naive schizophrenic patients:a high-resolution SPECT study. Psychiatry Research: Neuroimaging 90:159-168, 1999.
  • 정신분열병 환자들의 정서조절과정에 있어서의 특성
    한국심리학회지:임상 19/2 :269-279,2000
  • 여성 경도 알쯔하이머형 치매군, 치매의심군, 그리고 비치매 대조군간의 신경인지기능의 비교
    신경정신의학(Journal of the Korean Neuropsychiatric Association) 39/1 :167-182,2000
  • 한국판 양성 및 음성증후군 척도(Positive and Negative Syndrome Scale)의 신뢰도와 타당도
    신경정신의학(Journal of the Korean Neuropsychiatric Association) 40/0 :1090-1105,2001
  • 긍정적, 부정적 정서 자극에 의해 유발된 P3
    정신신체의학 9/0 :143-152,2001
  • 기분안정기의 I형 양극성 장애에서 신경인지기능
    신경정신의학 41/0 :638-648,2002
  • 정신분열병 약물 치료에 대한 한국형 알고리듬의 개발 계획
    대한정신약물학회지(Korean J Psychopharmacol) 14/0 :108-118,2003
  • 정신분열병에서 정서평가의 기능이상
    정신분열병클리닉(J Schinophrenia Clinics) 6/0 :132-136,2003
  • 정신분열병 환자의 인지과제수행에서 삼차원적 시공간-운동 방해자극 처리의 특성.
    신경정신의학(Journal of the Korean Neuropsychiatric Association) 42/0 :216-221,2003
  • Anger and coronary calcification in individuals with and without risk factors of coronary artery disease.
    YONSEI MEDICAL JOURNAL 43/0 :793-799,2003
  • Reduced P3 amplitudes by negative facial emotional photographs in schizophrenia.
    SCHIZOPHRENIA RESEARCH 64/0 :125-135,2003
  • 시각 자극 사건 관련 전위를 이용한 알코올 갈망의 신경 생리적 측정
    신경정신의학(Journal of the Korean Neuropsychiatric Association) 42/4 :466-475,2003
  • 주요 정신질환의 약물치료에 대한 한국형 알고리듬 개발
    대한정신약물학회지(Korean J Psychopharmacol) 13/0 :30-36,2003
  • 높은 양가감정을 보이는 정신분열병 환자의 증상 특성
    정신분열병클리닉(J Schinophrenia Clinics) 7/2 :73-50,2004
  • 한국형 정신분열병 약물 치료 알고리듬 개발을 위한 설문 조사
    대한정신약물학회지(Korean J Psychopharmacol) 15/2 :219-235,2004
  • Quetiapine의 정신분열증에 대한 효능 및 안전성에 관한 개방 연구
    대한정신약물학회지(Korean J Psychopharmacol) 15/1 :51-57,2004
  • Increased P3 amplitudes induced by alcohol-related pictures in patients with alcohol dependence
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 28/ :1317-1323,2004
  • 한국판 정신분열형 양가감정 척도(K-SAS)의 개발
    신경정신의학(Journal of the Korean Neuropsychiatric Association) 44/1 :58-64,2005
  • 만성 강박장애 환자의 정서처리 특성 : 정신분열병 환자 및 정상인과의 비교
    신경정신의학(Journal of the Korean Neuropsychiatric Association) 44/3 :311-318,2005
  • 알코올 의존 환자의 알코올 관련 자극에 대한 암묵적 정서 평가
    신경정신의학(Journal of the Korean Neuropsychiatric Association) 44/3 :334-341,2005
  • 알코올 의존 환자의 알코올 관련 자극에 대한 암묵적 정서 평가
    신경정신의학(Journal of the Korean Neuropsychiatric Association) 44/3 :334-341,2005
  • Aberrantly flattened responsivity to emotional pictures in paranoid schizophrenia
    PSYCHIATRY RESEARCH 143/ :135-145,2006
  • Behavioral evidence of blunted and inappropriate affective responses in schizophrenia: Lack of a negativity bias
    PSYCHIATRY RESEARCH 142/ :53-66,2006
  • Shape deformation of the insula in schizophrenia
    NEUROIMAGE 32/ :220-227,2006
  • Greater impairment in negative emotion evaluation ability in patients with paranoid schizophrenia
    YONSEI MEDICAL JOURNAL 47/3 :343-353,2006
  • Differences of photographs inducing craving between alcoholics and non-alcoholics
    YONSEI MEDICAL JOURNAL 47/4 :491-497,2006
  • 정서 사진에 대한 정서 반응성 : 평가 공간에서의 분포
    신경정신의학(Journal of the Korean Neuropsychiatric Association) 45/1 :28-33,2006
  • Neural substrates associated with evaluative processing during co-activation of positivity and negativity: A PET investigation
    BIOLOGICAL PSYCHOLOGY 73/ :253-261,2006
  • Alteration of brain metabolites in young alcoholics without structural changes
    NEUROREPORT 18/14 :1511-1514,2007
  • Neural Responses to Facial Expressions of Disgust but not Fear are Modulated by Washing Symptoms in OCD
    BIOLOGICAL PSYCHIATRY 61/9 :1072-1080,2007
  • Sex Differences in Neural Responses to Disgusting Visual Stimuli: Implications for Disgust-Related Psychiatric Disorders
    BIOLOGICAL PSYCHIATRY 62/5 :464-471,2007
  • Is a neutral face really evaluated as being emotionally neutral?
    Psychiatry Research 157/ :77-85,2008
  • Individual differences in disgust sensitivity modulate neural responses to aversive/disgusting stimuli
    European Journal Of Neuroscience 27/ :3050-3058,2008
  • 한국어판 모호한 의도-적개심 설문지 개발
    신경정신의학(Journal of the Korean Neuropsychiatric Association) 48/1 :29-35,2009
  • To discard or not to discard: the neural basis of hoarding symptoms in obsessive-compulsive disorder
    Molecular Psychiatry 14/ :318-331,2009
  • 양극성 조증 환자에서 언어, 얼굴, 장면 감정자극에 대한 정서 일치 편향:정상인 및 정신분열병 환자와의 비교
    대한정신약물학회지 20/3 :125-134,2009
  • 정신분열증 환자에서 정서유발단어에 의한 정서 반응성
    신경정신의학(Journal of the Korean Neuropsychiatric Association) 48/5 :328-335,2009
  • 젊은 성인에서 중립 얼굴표정 인식과 관련된 심리적 요인들
    신경정신의학(Journal of the Korean Neuropsychiatric Association) 48/6 :1-7,2009
  • Association of DRD4 and COMT Polymorphisms with Disgust Sensitivity in Healthy Volunteers
    NEUROPSYCHOBIOLOGY 61/2 :105-112,2010
  • Attribution bias in ultra-high risk for psychosis and first-episode schizophrenia
    Schizophrenia Research 118/1-3 :54-61,2010
  • What factors are related to delayed treatment in individuals at high risk for psychosis?
    EARLY INTERVENTION IN PSYCHIATRY 4/ :124-131,2010
  • A descriptive study of pathways to care of high risk for psychosis adolescents in Korea
    EARLY INTERVENTION IN PSYCHIATRY 4/ :119-123,2010
  • Perception bias of disgust in ambiguous facial expressions in obsessive-compulsive disorder
    Psychiatry Research 178/1 :126-131,2010
  • Genetic fuzzy classifier for sleep stage identification
    Computers In Biology And Medicine 40/7 :629-634,2010
  • Decreased P3 amplitudes elicited by negative facial emotion in manic patients: Selective deficits in emotional processing
    Neuroscience Letters 481/2 :92-96,2010
  • Psychotic Features as the First Manifestation of 22q11.2 Deletion Syndrome
    Psychiatry Investigation 7/ :72-74,2010
  • Status of the Early Psychosis Movement in Korea
    Journal of the Psychiatric Association of Thailand 55/2 :121-131,2010
  • 한국어 정서유발 단어집의 개발
    신경정신의학(Journal of the Korean Neuropsychiatric Association) 49/5 :468-479,2010
  • 한국인에서의 Ekman 얼굴 표정 사진의 신뢰도와 타당도
    우울조울병 8/2 :145-151,2010
  • The reliability and validity of the korean version of the structured interview for prodromal syndrome
    Psychiatry Investigation 7/4 :257-263,2010
  • Structural Brain Alterations in Individuals at Ultra-high Risk for Psychosis: A Review of Magnetic Resonance Imaging Studies and Future Directions
    JOURNAL OF KOREAN MEDICAL SCIENCE 25/12 :1700-1709,2010
  • Reduced visual P300 amplitudes in individuals at ultra-high risk for psychosis and first-episode schizophrenia
    Neuroscience Letters 486/ :156-160,2010
  • 정신분열병 환자의 주관적 및 객관적 인지 손상
    대한정신분열병학회지 13/1 :20-27,2010
  • Genetic fuzzy classifier for sleep stage identification
    Computers In Biology And Medicine 40/7 :629-634,2010
  • 알코올 의존 환자에서 사진자극과 문자자극에 대한 암묵적 연산결과 비교
    중독정신의학 14/2 :70-76,2010
  • Neurocognitive performance in subjects at ultrahigh risk for schizophrenia: a comparison with first-episode schizophrenia
    COMPREHENSIVE PSYCHIATRY 52/1 :33-40,2011
  • 백인과 일본인의 얼굴정서 자극에 대한 한국인의 인식 차이
    우울조울병 9/1 :17-23,2011
  • Differential priming effect for subliminal fear and disgust facial expressions
    ATTENTION PERCEPTION & PSYCHOPHYSICS 73/2 :473-481,2011
  • Coping Strategies and Their Relationship to Psychopathologies in People at Ultra High-Risk for Psychosis and With Schizophrenia
    JOURNAL OF NERVOUS AND MENTAL DISEASE 199/ :106-110,2011
  • Clinical efficacy of individual cognitive therapy in reducing psychiatric symptoms in people at ultra-high risk for psychosis
    EARLY INTERVENTION IN PSYCHIATRY 5/2 :174-178,2011
  • Associated Factors of Quality of Life in First-Episode Schizophrenia Patients
    PSYCHIATRY INVESTIGATION 8/3 :201-206,2011
  • Emotional Priming With Facial Exposures in Euthymic Patients With Bipolar Disorder
    JOURNAL OF NERVOUS AND MENTAL DISEASE 199/ :971-977,2011
  • Associated Factors of Quality of Life in First-Episode Schizophrenia Patients
    PSYCHIATRY INVESTIGATION 8/3 :201-206,2011
  • Longitudinal patterns of social functioning and conversion to psychosis in subjects at ultra-high risk
    AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY 45/9 :763-770,2011
  • Psychometric analysis of the Korean version of the Disgust Scale-Revised
    COMPREHENSIVE PSYCHIATRY 53/ :648-655,2012
  • FKBP5 polymorphisms as vulnerability to anxiety and depression in patients with advanced gastric cancer: A controlled and prospective study
    PSYCHONEUROENDOCRINOLOGY 37/ :1569-1576,2012
  • Differential alteration of automatic semantic processing in treated patients affected by bipolar mania and schizophrenia: An N400 study
    PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 38/2 :194-200,2012
  • Regional cortical thinning in subjects with high genetic loading for schizophrenia
    SCHIZOPHRENIA RESEARCH 141/1-3 :197-203,2012
  • Gamma oscillatory activity in relation to memory ability in older adults
    INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY 86/2 :58-65,2012
  • Aberrant Auditory Processing in Schizophrenia and in Subjetcs at Ultra-High-Risk for Psychosis
    SCHIZOPHRENIA BULLETIN 38/6 :1258-1267,2012
  • 조현병 및 정신증 고위험군에서의 작업기억 손상
    대한조현병학회지 15/2 :66-72,2012
  • Neural Evidence for Emotional Involvement in Pathological Alcohol Craving
    ALCOHOL AND ALCOHOLISM 48/3 :288-294,2013
  • Theta-gamma coupling during a working memory task as compared to a simple vigilance task
    NEUROSCIENCE LETTERS 532/6 :39-43,2013
  • Small-world networks in individuals at ultra-high risk for psychosis and first-episode schizophrenia during a working memory task
    NEUROSCIENCE LETTERS 535/1 :35-39,2013
  • Attributional Style in Healthy Persons: Its Association with 'Theory of Mind' Skills
    PSYCHIATRY INVESTIGATION 10/1 :34-40,2013
  • The relationship between psychosocial functioning and resilience and negative symptoms in individuals at ultra-high risk for psychosis.
    AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY 47/8 :762-771,2013
  • Genetic Influence of COMT and BDNF Gene Polymorphisms on Resilience in Healthy College Students
    NEUROPSYCHOBIOLOGY 68/3 :174-180,2013
  • 자아존중감과 의심의 상관성 : 정산군, 정신증 고위험군, 최근 발병 조현병군
    대한조현병학회지 16/2 :86-92,2013
  • Temperament and character in individuals at ultra-high risk for psychosis and with first-episode schizophrenia: Associations with psychopathology, psychosocial functioning, and aspects of psychological health
    COMPREHENSIVE PSYCHIATRY 54/8 :1161-1168,2013
  • APOLIPOPROTEIN E GENE POLYMORPHISM, ALCOHOLUSE, AND THEIR INTERACTIONS IN COMBAT-RELATEDPOSTTRAUMATIC STRESS DISORDER
    DEPRESSION AND ANXIETY 30/12 :1194-1201,2013
  • 일 대학병원 정신증 환자에서 항정신병약물 병용요법의 사용
    대한정신약물학회지 24/2 :69-75,2013
  • Antipsychotic polypharmacy and high-dose prescription in schizophrenia: a 5-year comparison
    AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY 48/1 :52-60,2014
  • Reduced Binding Potential of GABA-A/Benzodiazepine Receptors in Individuals at Ultra-high Risk for Psychosis:An [18F]-Fluroflumazenil Positron Emission Tomography Study
    SCHIZOPHRENIA BULLETIN 40/3 :548-557,2014
  • Distinct functional connectivity of limbic network in the washing type obsessive-compulsive disorder
    PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 53C/ :149-155,2014
  • 정신증 고위험군과 조현병 환자에서 정서조절곤란, 귀인편향, 신경인지손상결핍 : 편집증과의 관계
    대한조현병학회지 17/2 :63-71,2014
  • 국내 일 병원 중환자실에서 관찰한 섬망 환자의 예후
    신경정신의학 53/6 :418-425,2014
  • Theory of Mind as a Mediator of Reasoning and Facial Emotion Recognition: Findings from 200 Healthy People
    PSYCHIATRY INVESTIGATION 11/2 :105-111,2014
  • Neurocognitive impairments in individuals at ultra-high risk for psychosis: Who will really convert?
    AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY 49/5 :462-470,2015
  • Impaired facial emotion recognition in individuals at ultra-high risk for psychosis and with first-episode schizophrenia, and their associations with neurocognitive deficits and self-reported schizotypy
    SCHIZOPHRENIA RESEARCH 165/1 :60-65,2015
  • Relationships between chronotypes and affective temperaments in healthy young adults
    JOURNAL OF AFFECTIVE DISORDERS 175/- :256-259,2015
  • The Impact of Coping Styles on Psychological Distress and Quality of Life in Korean Patients with Cancer
    Korean Journal of Psycho-Oncology(정신종양학회지) 1/1 :36-42,2015
  • Experiential pleasure deficits in the prodrome: A study of emotional experiences in individuals at ultra-high risk for psychosis and recent-onset schizophrenia
    COMPREHENSIVE PSYCHIATRY 68/ :209-216,2016
  • Frontostriatal Connectivity Changes in Major Depressive Disorder After Repetitive Transcranial Magnetic Stimulation: A Randomized Sham-Controlled Study.
    JOURNAL OF CLINICAL PSYCHIATRY 77/9 :e1137-e1143,2016
  • Heterogeneity of Psychosis Risk Within Individuals at Clinical High Risk A Meta-analytical Stratification: AMeta-analytical Stratification
    JAMA PSYCHIATRY 73/2 :113-120,2016
  • Common variants of HTR3 genes are associated with obsessive-compulsive disorder and its phenotypic expression
    SCIENTIFIC REPORTS 6/32564 :1-8,2016
  • Associations between actigraphy-assessed sleep, inflammatory markers, and insulin resistance in the Midlife Development in the United States (MIDUS) study
    SLEEP MEDICINE 27-28/ :72-79,2016
  • 조현병 환자에서의 폭력행동
    Journal of the Korean Medical Association 59/1975-8 :947-952,2016
  • Impaired social and role function in ultra-high risk for psychosis and first-episode schizophrenia: Its relations with negative symptoms
    PSYCHIATRY INVESTIGATION 14/2 :186-192,2017
  • Prevalence of Metabolic Syndrome in Patients with Schizophrenia in Korea: A Multicenter Nationwide Cross-Sectional Study
    PSYCHIATRY INVESTIGATION 14/1 :44-50,2017

저서

  • 안석균. 잘못된 기억과 신념의 인지적 뇌기전. In: 권준수, 김성윤, 김승현, 김재진, 김창윤, 류인균, 배재남, 신민섭, 안석균, 이선우, 이창욱, 하규섭. 뇌와 기억 그리고 신념의 형성.
  • 시그마프레스, 서울, 2004.1.
  • 안석균. 개론: 사회인지와 정신분열병의 모델. In: 사회인지와 정신분열병. 중앙문화진수
  • 출판사, 서울, 2004.
  • 이만홍, 안석균: 통합재활치료의 개발. In: 정신분열병의 통합재활치료. 하나의학사, 서울, pp15-46, 1999
  • 이희상, 안석균, 유계준: 인지분화훈련 프로그램. In: 정신분열병의 통합재활치료(이만홍, 유계준, 이희상, 조현상, 안석균, 박소라, 서진환), 하나의학사, 서울, pp47-85, 1999

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