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소속

  • 정형외과학교실

보직

  • 세브란스병원 척추류마티스통증센터 소장

직위

  • 교수

연구실 위치

  • 의과대학 구관 432호

전화/팩스

  • 02) 2228-2191 /

학력사항

  • 연세대학교 의학과 학사 (1981)
    연세대학교 대학원 의학석사 (1984)
    연세대학교 대학원 의학박사 (1992)

교육 및 연구 경력

  • 1991-1992 연세대학교 의과대학 정형외과학교실 전임강사
    1993-1995 Research Associate, University of Iowa 연수
    1993-1997 연세대학교 의과대학 정형외과학교실 조교수
    1998-2002 연세대학교 의과대학 정형외과학교실 부교수
    2003-현재 연세대학교 의과대학 정형외과학교실 교수

기타 학술 관련 경력

  • 대한정형외과학회
    대한척추외과
    International Society for the Study of the Lumbar Spine
    Orthopaedic Research Society
    North American Spine Society
    Advisory Board, Spine

연구,관심분야

  • 요통기전
    추간판 변성 및 재생

강의분야

  • 척추외과

논문

  • Sexual dysfunction in men with paraparesis in lumbar burst fractures
    SPINE 25/17 :2187-2190,2000
  • Unilateral versus Bilateral Pedicle Screw Fixation in Lumbar Spinal Fusion
    SPINE 25/0 :1843-1847,2000
  • 요추 척추관 협착증의 병태생리
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 1/0 :100-105,2000
  • 흉요추 골절환자에서 자기공명영상을 이용한 후방인대 복합체 손상의 진단
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 1/0 :70-76,2000
  • Reliability of Magnetic Resonance Imaging in Detecting Posterior Ligament Complex Injury in Thoracolumbar Spinal Fractures
    SPINE 25/0 :2079-2083,2000
  • Deep Vein Thrombosis after Major Spinal Surgery
    SPINE 25/0 :1827-1830,2000
  • Recurrent lumbar disc herniation
    SPINE 26/6 :672-676,2001
  • Comparison between PLF with pedicle screw fixation and anterior interbody fusion with pedicle screw fixation in adult spondylolytic sponlylolisthesis
    YONSEI MEDICAL JOURNAL 42/3 :316-323,2001
  • Lumbosacral scoliotic list by lumbar disc herniation
    SPINE 26/6 :667-671,2001
  • 골 형성 유전자 치료 (제5형 Adenoviral vector를 이용한 Ex Vivo 유전자 치료로 척추 유합 시도시 면역학적 모델)
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 8/4 :437-446,2001
  • Feasibility of ultrasound examination in posterior ligament complex injury of thoracolumbar spine fracture
    SPINE 27/19 :2154-2158,2002
  • 추간판 세포에서 Transforming Growth Factor-β1 및 Bone Morphogenetic Protein-2 에 의한 기질 생성 및 연골형 표현형 발현
    대한척추외과학회지(Journal of Korean Society of Spine Surgery) 9/3 :165-171,2002
  • Cefatriaxone induced immune hemolytic anemia
    YONSEI MEDICAL JOURNAL 43/3 :391-394,2002
  • Comparison between PLF with pedicle screw fixation and AIF with pedicle screw fixation
    YONSEI MEDICAL JOURNAL 42/3 :316-323,2002
  • 척추 황색 인대 세포에서 Bone Morphogenetic Protein-2 cDNA 전달에 의한 골형성 유도 : 조직 공학적 접근의 가능성
    대한척추외과학회지(Journal of Korean Society of Spine Surgery) 9/4 :263-269,2002
  • 가토의 추간판 세포 삼차원 배양에서 교원질 농도 변화에 따른 추간판 세포의 기질 생성반응
    대한척추외과학회지(Journal of Korean Society of Spine Surgery) 9/2 :70-77,2002
  • 추간판내 유전자 전달에 의한 전신 면역 반응
    대한척추외과학회지(Journal of Korean Society of Spine Surgery) 9/1 :84-90,2002
  • 두부 손상이 골절치유 촉진시 동물모델 및 유전자 발현 분석
    대한정형외과연구학회지(Journal Of Korean Orthopaedic Research Society) 6/2 :117-185,2003
  • 이중에너지 흡수계측기를 이용한 골다공증성 척추 골절의 평가 - 방사선적 형태계측법과의 비교 -
    대한골대사학회지 11/1 :35-41,2004
  • 인간 추간판 세포에서 파미드로네이트의 기질 생성 및 세포 사멸 효과
    대한골대사학회지 11/2 :121-128,2004
  • 자가 장골을 이용한 흉요추부 추체간 전방 유합술시 이식 장골 공여부 재건술 후 추시 결과
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 11/1 :31-,2004
  • 저 파동성 전자기장이 인간 추간판 세포에 미치는 영향
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 11/4 :194-201,2004
  • 중간엽 줄기세포를 이용한 추간판내 유전자 치료 : 퇴행성 추간판 질환에서 치료적 의미
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 11/2 :67-76,2004
  • 척추 및 슬관절의 퇴행성 변화와 요추 골밀도의 상관관계
    대한골대사학회지 11/2 :167-172,2004
  • Biologic Modification of Ligamentum Flavum Cells by Marker Gene Transfer and Recombinant Human Bone Morphogenetic Protein-2
    SPINE 29/9 :960-965,2004
  • The effects of ketorolac injected via patient controlled analgesia postoperatively on spinal fusion
    YONSEI MEDICAL JOURNAL 46/2 :245-251,2005
  • Dexamethasone과 Transforming Growth Factor-Beta 1에 의한 인간 추간판 세포의 표현형 유지 및 기질 생성
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 12/2 :91-100,2005
  • Intradiscal electrothermal treatment for chronic lower back pain patients with internal disc disruption
    YONSEI MEDICAL JOURNAL 46/4 :539-545,2005
  • 한국어판 Oswestry Disability Index(장애지수)의 문화적 개작
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 12/2 :146-152,2005
  • 요통에 대한 Neurotropin 투여의 진통효과 및 안전성 평가를 위한 다기관, 이중맹검, Aceclofenac 비교 임상시험
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 12/3 :214-223,2005
  • 아텔로콜라겐 지지체와 성장인자에 의한 조직 공학적 추간판의 재생
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 12/3 :164-173,2005
  • De novo osteogenesis from human ligamentum flavum by adenovirus-mediated bone morphogenetic protein-2 gene transfer
    SPINE 30/24 :2749-2754,2005
  • 만성 요통에 대한 Tramadol 37.5mg/Acetaminophen 325mg 복합제제와 Cyclo-Oxygenase-2(Celecoxib) 억제제의 유효성 및 안전성 비교 연구 -다기관, 무작위 배정, 비교 임상 연구-
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 12/4 :299-309,2005
  • 심한 비특발성 척추측만증 환자에서 수술 전,후 폐 기능 변화
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 13/2 :106-113,2006
  • Optimal end-tidal concentration of sevoflurane to test an ankle clonus in children
    SPINE 31/ :E813-E816,2006
  • Case Reports: Cervical Myelopathy from Atlantal Hypoplasia and Torticollis
    Clinical Orthopaedics and Related Research 451/ :274-278,2006
  • A Comparison of Autologous and Homologous Transfusions in Spinal Fusion
    YONSEI MEDICAL JOURNAL 47/6 :840-846,2006
  • 민간 BMP-2-생리기능 복합 바이오활성 세라믹스를 이용한 조골 세포 분화 유도
    대한정형외과학회지 42/3 :386-394,2007
  • The incidence of new vertebral compression fractures in women after kyphoplasty and factors involved
    YONSEI MEDICAL JOURNAL 48/4 :645-652,2007
  • 정상 한국인 요추 추간판 높이의 방사선학적 계측
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 14/3 :129-136,2007
  • 퇴행 비후된 척추 후관절이 황색인대의 섬유화 및 골화에 미치는 영향
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 13/ :-,2007
  • 청소년기 특발성 척추 측만증과 신경근육성 척추 측만증에서의 골밀도 비교
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 14/1 :17-24,2007
  • Paraspinal Abscess Communicated with Epidural Abscess after Extra-Articular Facet Joint Injection
    YONSEI MEDICAL JOURNAL 48/4 :711-714,2007
  • The Association of the Activation-Inducible Tumor Necrosis Factor Receptor and Ligand with Lumbar Disc Herniation
    YONSEI MEDICAL JOURNAL 48/5 :839-846,2007
  • Calcium phosphate nano-composite with bone morphogenetic protein
    KEY ENGINEERING MATERIALS 330-332/ :361-364,2007
  • Biologic response of human intervertebral disc cells to gene therapy cocktail
    Spine 33/ :1850-1855,2008
  • Life expectancy after lumbar spine surgery - One- to eleven-year follow-up of 1015 patients
    Spine 33/ :2116-2121,2008
  • 흉강경을 이용한 척추측만증 수술에서의 굵은 강봉-다중축 나사못과 가는 강봉-단중축 나사못 비교
    대한척추외과학회지(Journal Of Korean Society Of Spine Surgery) 15/1 :9-17,2008
  • 정형외과 외래 진료에서 골다공증 진단 및 치료지침의 진료양상 및 국내 치료지침의 문제점
    대한골대사학회지 14/1 :49-57,2008
  • Risk factors associated with the halo phenomenon after lumbar fusion surgery and its clinical significance
    Asian Spine Journal 2/1 :22-26,2008
  • Bone Metabolism in Postmenopausal Women With Lumbar Spinal Stenosis Analysis of Bone Mineral Density and Bone Turnover Markers
    Spine 33/ :2435-2439,2008
  • Diabetes and smoking as prognostic factors after cervical laminoplasty
    Journal Of Bone And Joint Surgery-British Volume 90B/ :1468-1472,2008
  • JCI(Joint Commission International) 인증 경험
    한국의료Qa학회지 14/1 :29-34,2008
  • QA활동과 식스시그마
    한국의료Qa학회지 14/2 :45-57,2008
  • A validated finite element analysis of nerve root stress in degenerative lumbar scoliosis
    Medical & Biological Engineering & Computing 47/6 :599-605,2009
  • Comparison of mechanical motion profiles following instrumented fusion and non-instrumented fusion at the L4-5 segment
    Clinical And Investigative Medicine 32/1 :64-69,2009
  • Zonal responsiveness of the human intervertebral disc to bone morphogenetic protein-2
    Spine 34/17 :1834-1838,2009
  • Comparison of Surgical Outcomes in Thoracolumbar Fractures Operated with Posterior Constructs Having Varying Fixation Length with Selective Anterior Fusion
    Yonsei Medical Journal 50/4 :546-554,2009
  • 20-year-follow up of treatment using spine osteotomy and halo-pelvic traction for tuberculous kyphosis
    Asian Spine Journal 3/1 :27-31,2009
  • multiple levels of lumbar spondylolysis
    Asian Spine Journal 3/1 :35-38,2009
  • Restoration of Bone Turnover Rate After Decompression Surgery in Patients With Symptomatic Lumbar Spinal Stenosis Preliminary Report
    Spine 34/8 :E635-E639,2009
  • 시멘트 보강술을 시행한 골다공증성 척추 골절 환자에서 리세드로네이트, 알렌드로네이트와 칼슘 카보네이트 약물치료 후 발생하는 척추 골절의 비교 연구
    대한정형외과학회지 44/4 :436-441,2009
  • 극돌기 절골술과 추궁판 절제술에 대한 생체역학적 비교
    대한기계학회논문집 A 33/7 :645-651,2009
  • Tissue Engineering of the Intervertebral Disc with Cultured Nucleus Pulposus Cells Using Atelocollagen Scaffold and Gene Therapy
    Journal Of Korean Society Of Spine Surgery(대한척추외과학회지) 17/2 :49-56,2010
  • Clinical Outcome of the Operative Treatment for Lumbar Degenerative Spondylopathy in Patients Undergoing Dialysis
    Journal Of Korean Society Of Spine Surgery(대한척추외과학회지) 17/2 :97-103,2010
  • Video-Assisted Thoracoscopic Surgery for Correction of Adolescent Idiopatic Scoliosis: Comparison of 4.5 mm versus 5.5 mm Rod Constructs
    YONSEI MEDICAL JOURNAL 51/5 :753-760,2010
  • Analysis of biomechanical changes after removal of instrumentation in lumbar arthrodesis by finite element analysis
    Medical & Biological Engineering & Computing 48/7 :703-709,2010
  • The relation between rotation deformity and nerve root stress in lumbar scoliosis
    International Journal Of Modern Physics B 24/15-16 :2803-2808,2010
  • Vascular Injury in Thoracolumbar Spinal Surgeries and Role of Angiography in Early Diagnosis and Management
    Journal Of Spinal Disorders & Techniques 23/6 :418-424,2010
  • Pulsed Electromagnetic Field Stimulates Cellular Proliferation in Human Intervertebral Disc Cells
    YONSEI MEDICAL JOURNAL 51/6 :954-959,2010
  • Antibiotic Microbial Prophylaxis for Spinal Surgery: Comparison between 48 and 72-Hour AMP Protocols
    Asian Spine Journal 4/2 :71-76,2010
  • Delayed Spinal Epidural Hematoma after En Block Spondylectomy for Vertebral Ewing's Sarcoma
    Asian Spine Journal 4/2 :118-122,2010
  • Comparison between Operated Muscular Dystrophy and Spinal Muscular Atrophy Patients in terms of Radiological, Pulmonary and Functional Outcomes
    Asian Spine Journal 4/2 :82-88,2010
  • Video-Assisted Thoracoscopic Surgery Plus Lumbar Mini-Open Surgery for Adolescent Idiopathic Scoliosis
    YONSEI MEDICAL JOURNAL 52/1 :130-136,2011
  • Pelvic Obliquity in Neuromuscular Scoliosis Radiologic Comparative Results of Single-Stage Posterior Versus Two-Stage Anterior and Posterior Approach
    SPINE 36/2 :146-152,2011
  • The Risk Assessment of a Fall in Patients With Lumbar Spinal Stenosis
    SPINE 36/9 :E588-E592,2011
  • The Quantitative Assessment of Risk Factors to Overstress at Adjacent Segments After Lumbar Fusion Removal of Posterior Ligaments and Pedicle Screws
    SPINE 36/17 :1367-1373,2011
  • Value of Preoperative Pulmonary Function Test in Flaccid Neuromuscular Scoliosis Surgery
    SPINE 36/21 :1391-1394,2011
  • 요추부 척추관 협착증을 가진 50세 이상 여자 환자의 골다공증 또는 슬관절 퇴행성 관절염의 유병율
    대한골대사학회지 18/1 :33-38,2011
  • Tissue Engineering of the Intervertebral Disc With Cultured Nucleus Pulposus Cells Using Atelocollagen Scaffold and Growth Factors
    SPINE 37/6 :452-458,2012
  • Prevalence of hip pathology in patients over age 50 with spinal conditions requiring surgery
    INDIAN JOURNAL OF ORTHOPAEDICS 46/ :291-296,2012
  • Osteoporotic profiles in elderly patients with symptomatic lumbar spinal canal stenosis
    INDIAN JOURNAL OF ORTHOPAEDICS 46/ :279-284,2012
  • Transpedicular Curettage and Drainage of Infective Lumbar Spondylodiscitis: Technique and Clinical Results
    Clinics in Orthopedic Surgery 4/3 :200-208,2012
  • Surgical Outcome of Lumbar Fusion Surgery in Patients With Parkinson Disease
    JOURNAL OF SPINAL DISORDERS & TECHNIQUES 25/ :351-355,2012
  • Changes in Vitamin D Status After Surgery in Female Patients With Lumbar Spinal Stenosis and Its Clinical Significance
    SPINE 37/21 :1326-1330,2012
  • The Biomechanical Effect of Pedicle Screws' Insertion Angle and Position on the Superior Adgacent Segment in 1 Segment Lumbar Fusion
    SPINE 37/19 :1637-1644,2012
  • Joint Commission International 인증의 의미
    JOURNAL OF THE KOREAN MEDICAL ASSOCIATION 55/1 :17-22,2012
  • Prognostic Factor Analysis in Patients with Metastatic Spine Disease Depending on Surgery and Conservative Treatment: Review of 577 Cases
    ANNALS OF SURGICAL ONCOLOGY 20/1 :40-46,2013
  • Inflammatory Cytokines Induce Fibrosis and Ossification of Human Ligamentum Flavum Cells
    JOURNAL OF SPINAL DISORDERS & TECHNIQUES 26/1 :E6-E12,2013
  • The Natural History of Degenerative Spondylolisthesis of the Cervical Spine With 2-to 7-Year Follow-up
    SPINE 38/4 :E205-E210,2013
  • Analysis of Single Nucleotide Polymorphism in Adolescent Idiopathic Scoliosis in Korea:For Personalized Treatment
    YONSEI MEDICAL JOURNAL 54/2 :500-509,2013
  • Prevalence of Vitamin D Deficiency in Patients with Lumbar Spinal Stenosis and its Relationship with Pain
    PAIN PHYSICIAN 16/2 :165-176,2013
  • Pre-Emptive and Multi-Modal Perioperative Pain Management May Improve Quality of Life in Patients Undergoing Spinal Surgery (Observational Study)
    PAIN PHYSICIAN 16/ 3 :E217-E226,2013
  • Loss of Lordosis and Clinical Outcomes after Anterior Cervical Fusion with Dynamic Rotaional Plates
    YONSEI MEDICAL JOURNAL 54/3 :726-731,2013
  • Neurologic Recovery According to the Spinal Fracture Patterns by Denis Classification.
    YONSEI MEDICAL JOURNAL 54/3 :715-719,2013
  • The Effect of Age on Cervical Sagittal Alignment: Normative Data on 100 Asymptomatic Subjects
    SPINE 38/8 :E458-E463,2013
  • Patient safety in spine surgery: regarding the wrong-site surgery.
    Asian Spine Journal 7/1 :63-71,2013
  • Comparison of adjacent segment degeneration after successful posterolateral fusion with unilateral or bilateral pedicle screw instrumentation: a minimum 10-year follow-up
    SPINE JOURNAL 13/ :1208-1216,2013
  • Joint Laxity Negatively Correlates With Lumbar Disc Degeneration in Young Adults
    SPINE 38/24 :E1541-E1547,2013
  • Cervical Foraminal and Discal Height after Dynamic Rotational Plating in the Cervical Discectomy and Fusion
    Asian Spine Journal 7/4 :289-293,2013
  • Down-Regulation of Collagen Synthesis and Matrix Metalloproteinase Expression in Myofibroblasts from Dupuytren Nodule Using Adenovirus-Mediated Relaxin Gene Therapy
    JOURNAL OF ORTHOPAEDIC RESEARCH 32/4 :515-523,2014
  • Transpedicular curettage and drainage versus combined anterior and posterior surgery in infectious spondylodiscitis
    INDIAN JOURNAL OF ORTHOPAEDICS 48/Issue :74-80,2014
  • Functional Outcomes in Duchenne Muscular Dystrophy Scoliosis Comparison of the Differences Between Surgical and Nonsurgical Treatment
    JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME 96/5 :409-415,2014
  • The Prevalence of Idiopathic Scoliosis in Eleven Year-Old Korean Adolescents: A 3 Year Epidemiological Study
    YONSEI MEDICAL JOURNAL 55/3 :773-778,2014
  • 요추 추간판 탈출증 환자의 수술적 치료에서 수술전 자기 공명 영상 검사 소견과 수술적 치료 결과의 관계
    대한척추외과학회지 21/1 :24-29,2014
  • Facet joint degeneration of the cervical spine: A computed tomographic analysis of 320 patients
    SPINE 39/12 :E713-E718,2014
  • Perioperative complication and surgical outcome in patients with spine metastases: Retrospective 200-case series in a single institute
    CLINICAL NEUROLOGY AND NEUROSURGERY 122/- :80-86,2014
  • Age-related changes in cervical sagittal range of motion and alignment
    Global Spine Journal 4/3 :151-156,2014
  • Herniated Intervertebral Disk Induces Hypertrophy and Ossification of Ligamentum Flavum
    JOURNAL OF SPINAL DISORDERS & TECHNIQUES 27/7 :382-389,2014
  • Comparison of effects of nonoperative treatment and decompression surgery on risk of patients with lumbar spinal stenosis falling: Evaluation with functional mobility tests
    JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME 96/13 :e110(1)-e110(6),2014
  • At Least One Cyclic Teriparatide Administration Can Be Helpful to Delay Initial Onset of a New Osteoporotic Vertebral Compression Fracture
    YONSEI MEDICAL JOURNAL 55/6 :1576-1583,2014
  • Quality of life in patients with osteoporotic vertebral fractures
    Asian Spine Journal 8/5 :653-658,2014
  • Quality of life comparison between vertebroplasty and kyphoplasty in patients with osteoporotic vertebral fractures
    Asian Spine Journal 8/6 :799-803,2014
  • Safety evaluation of freehand lateral mass screw fixation in the subaxial cervical spine: Evaluation of 1256 screws
    SPINE 40/1 :2-5,2015
  • Finite Element Analysis for Comparison of Spinous Process Osteotomies Technique with Conventional Laminectomy as Lumbar Decompression Procedure
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