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소속

  • 신경외과학교실

직위

  • 임상교수

연구실 위치

  • ABMRC 523호

전화/팩스

  • 02-2228-2152 /

학력사항

  • 1995 가톨릭대학교 의과대학 의학과 (학사)
    1999 가톨릭대학교 의과대학 대학원 (의학석사)
    2005 가톨릭대학교 의과대학 대학원 (의학박사)

교육 및 연구 경력

  • 2003~2005 삼성서울병원 신경외과 임상강사
    2005~2009 가톨릭대학교 의과대학 의정부성모병원 신경외과 조교수/부교수
    2007~2009 미국 M.D. Anderson Cancer Center Post-Doc
    2010~2012 가톨릭대학교 의과대학 서울성모병원 신경외과 부교수
    2012~2015 연세대학교 의과대학 신경외과 부교수
    2015~ 연세대학교 의과대학 신경외과 교수

기타 학술 관련 경력

  • -수상내역-
    2004.10 대한신경외과학회 신경계 종양부분 최우수 논문상(심보성교수상)
    2004.11 아시아신경종양학회 젊은의학자상
    2005.07 대한뇌종양학회 뇌종양 기초 연구분야 최우수 논문상
    2005.10 세계소아신경외과학회 Anthony J. Raimondi ISPN Award
    2006.12 가톨릭의대 신경외과학교실 남천학술상
    2007.02 대한임상종양학회 춘계학술대회 학술상
    2007.04 대한신경외과학회 보령제약학술상
    2010.03 가톨릭의대 의학과 선택과정 교육우수교원
    2011.06 대한뇌종양학회 최우수 학술지상
    2013.06 대한소아뇌종양학회 아해 우수연구상
    2013.07 대한뇌종양학회 학술상 (기초연구부분 최우수 논문)


    -학회활동-
    대한신경외과학회 정회원 (전 학술간사)
    대한신경종양학회 정회원 (역형성 성상세포종위원회 위원장, 학술위원)
    대한뇌종양학회 (감사, 학술위원)
    미국신경종양학회 정회원
    유럽신경종양학회 정회원
    대한암학회 정회원
    암줄기세포연구회 정회원 (발기인)
    세계소아신경외과학회 정회원
    대한소아신경외과학회 정회원 (이사)
    대한소아뇌종양학회 정회원 (전 학술이사)
    Child's Nervous System Editorial Board Member

연구,관심분야

  • 뇌종양
    신경교종, 교모세포종
    뇌전이암
    신약 표적발굴 (뇌암줄기세포, 암미세환경)
    뇌종양 이행성연구 및 개인 맞춤형 정밀 뇌암치료 (유전자 기반 암치료)

논문

  • Staged Decompression of Chiari I Malformation Associated with Basilar Invagination. Kang SG, Jeun SS, Lee IW, Park CK, Hong YK, Kim MC, Kang JK: J Korean Neurosurg Soc 1998:27(10):1429-1433
  • Influence of Brain edema on the Antiischemic Effect of D-CPPene in Rat Focal Cerebral Infarction. Kang SG, Park CK, Kang JK: J Korean Neurosurg Soc 1999:28(8):1075-1081
  • Effect of Brain Oedema in the Measurement of Ischaemic Brain Damage in Focal Cerebral Infarction. Park CK, Kang SG. Acta Neurochir Suppl. 2000;76:269-271.
  • Lymphokine Activated Killer Cells from Umbilical Cord Blood Show Higher Antitumor Effect against Anaplastic Astrocytoma Cell Line (U87) and Medulloblastoma Cell Line (TE671) than Lymphokine Activated Killer Cells from Peripheral Blood. Kang SG, Ryu CH, Jeun SS, Park CK, Shin HJ, Kim JH, Kim MC, Kang JK. Childs Nerv Syst. 2004;20(3):154-162.
  • Surgical Approaches of Lateral Ventricle Tumors. Kang SG, Park K: J Korean Brain Tumor Soc 2004:3(2):82-87
  • Clinical and Radiological Prognostic Factors of Anaplastic Oligodendroglioma Treated by Combined Therapy. Neurol Med Chir (Tokyo). 2005 45(5):232-238; discussion 238-239.
  • Cytotoxicity of rat marrow stromal cells against malignant glioma cells. Childs Nerv Syst. 2005 21(7):528-538.
  • Interpretation of Wada Test in Anterior Temporal Lobectomy. J of The Kor Soc of Ster and Func Neurosur 2005:1(1):20-24
  • Combination celecoxib and temozolomide in C6 rat glioma orthotopic model. Oncol Rep. 2006 Jan;15(1):7-13.
  • Coexisting intracranial meningeal melanocytoma, dermoid tumor, and Dandy-Walker cyst in a patient with neurocutaneous melanosis. J Neurosurg. 2006 104(3):444-447.
  • Merlin inhibits growth hormone-regulated Raf-ERKs pathways by binding to Grb2 protein. Biochem Biophys Res Commun. 2006 24;340(4):1151-1157.
  • Effects of Hydroxycholroquine Co-administrated with Chemotherapeutic Agents on Malignant Glioma Cell Lines: in vitro Study. J Korean Neurosurg Soc. 2006 39(4):317-317 letter to editor
  • Multiple stem cell traits of expanded rat bone marrow stromal cells. Exp Neurol. 2006 199(2):416-26.
  • Diagnostic method for differentiating external hydrocephalus from simple subdural hygroma. J Neurosurg. 2006 105(1):65-70.
  • Combined direct anastomosis and encephaloduroarteriogaleosynangiosis using inverted superficial temporal artery-galeal flap and superficial temporal artery-galeal pedicle in adult moyamoya disease Surg Neurol. 2006 66(4):389-394; discussion 395.
  • Clinical images: Myositis ossificans of the upper extremity. Arthritis Rheum. 2007 56(7):2454.
  • Tethered cord syndrome; Surgical indication, technique and outcome. J Korean Neurosurg Soc. 2007 42(2):77-82.
  • Sudden cortical blindness in an adult with moyamoya disease. Surg Neurol. 2007 67(3):303-307.
  • Simple excision and periosteal reattachment for the treatment of calcified cephalhematoma - Technical note. J Neurosurg. 2007 106(2 Suppl):162-4.
  • Pituitary abscess in a pregnant woman. J Clin Neurosci. 2007 14(11):1135-1139.
  • Provisional experiences about KSPNO-G051, KSPNO-G052 protocols for the treatment of central nervous system germ cell tumors. J Korean Soc Pediatric Neurosurg 2007 4(1):57-66
  • Surgical results in pediatric moyamoya disease: Angiographic revascularization and the clinical results. Clin Neurol Neurosurg. 2007 109(2):125-31.
  • Clinical and radiographie results of unilateral transpedicular balloon kyphoplasty for the treatment of osteoporotic vertebral compression fractures. Acta Neurochir Suppl. 2008;101:157-60.
  • Cranioplasty effect on the cerebral hemodynamics and cardiac function. Acta Neurochir Suppl. 2008;102:15-20.
  • Cytotoxicity of human umbilical cord blood-derived mesenchymal stem cells against human malignant glioma cells. Childs Nerv Syst. 2008 24(3):293-302.
  • Comparison of the effect of decompressive craniectomy on different neurosurgical diseases. Acta Neurochir (Wien). 2009 151(1):21-30.
  • Risk Factors and Surgical Treatment for Symptomatic Adjacent Segment Degeneration after Lumbar Spine Fusion. J Korean Neurosurg Soc. 2009 46(5):425-430.
  • Ruptured right posterior inferior cerebellar artery aneurysm associated with hypoplasia of the right vertebral artery and both internal carotid arteries. Br J Neurosurg. 2009;23(5):551-553.
  • Surgical Management and Outcome of Tethered Cord Syndrome in School-Aged Children, Adolescents, and Young Adults. J Korean Neurosurg Soc. 2009 46(5):468-471.
  • Atypical choroid plexus papilloma of fourth ventricle in adult. J Korean Brain Tumor Soc 2009 8:101-104
  • Pituitary Teratoma Presenting as Central Diabetes Insipidus with a Normal MRI Finding. Yonsei Med J. 2010 51(2):293-294.
  • Therapeutic results of intra-arterial thrombolysis after full-dose intravenous tissue plasminogen activator administration. Am J Neuroradiol. 2010 31(8):1536-1540.
  • Spinal cord injury in cervical spinal stenosis by minor trauma. World Neurosurg. 2010 73(1):50-52; discussion e4.
  • Intended subtotal resection followed by radiosurgery for large vestibular schwannoma: single institute observational study. J Korean Brain Tumor Soc 2010:9: 97-102
  • Isolation and Perivascular Localization of Mesenchymal Stem Cells From Mouse Brain. Neurosurgery. 2010 67(3):711-720.
  • The Clinical Features of Spinal Leptomeningeal Dissemination from Malignant Gliomas. J Korean Neurosurg Soc. 2011 49(6):334-338.
  • Inhibition of STAT3 reverses drug resistance acquired in temozolomide-resistant human glioma cells. Oncol Lett 2011 2(1): 115-121
  • The onodi cell: an obstacle to sellar lesions with a transsphenoidal approach. Otolaryngol Head Neck Surg. 2011 145(6):1040-1042.
  • Presence of glioma stroma mesenchymal stem cells in a murine orthotopic glioma model. Childs Nerv Syst. 2011 27(6):911-922
  • C-Jun N-terminal kinase has a pivotal role in the maintenance of self-renewal and tumorigenicity in glioma stem-like cells
    ONCOGENE 31/44 :4655-4666,2012
  • Isolation of glioma cancer stem cells in relation to histological grades in glioma specimens.
    CHILDS NERVOUS SYSTEM 29/2 :217-229,2013
  • Postoperative nasal symptoms associated with an endoscopic endonasal transsphenoidal approach
    EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY 270/4 :1355-1359,2013
  • Changes in the biological characteristics of glioma cancer stem cells after serial in vivo subtransplantation.
    CHILDS NERVOUS SYSTEM 29/1 :55-64,2013
  • Existence of glioma stroma mesenchymal stemlike cells in Korean glioma specimens
    CHILDS NERVOUS SYSTEM 29/4 :549-563,2013
  • Increased in vivo angiogenic effect of glioma stromal mesenchymal stem-like cells on glioma cancer stem cells from patients with glioblastoma
    INTERNATIONAL JOURNAL OF ONCOLOGY 42/5 :1754-1762,2013
  • A novel 2-pyrone derivative, BHP, impedes oncogenic KRAS-driven malignant progression in breast cancer
    CANCER LETTERS 337/1 :49-57,2013
  • Isolation of mesenchymal stem-like cells in meningioma specimens
    INTERNATIONAL JOURNAL OF ONCOLOGY 43/4 :1260-1268,2013
  • Bilateral Nasoseptal Flaps for Endoscopic Endonasal Transsphenoidal Approach
    JOURNAL OF CRANIOFACIAL SURGERY 24/ :1569-1572,2013
  • Fractionated radiation-induced nitric oxide promotes expansion of glioma stem-like cells
    CANCER SCIENCE 104/ :1172-1177,2013
  • Isolation of tumor spheres and mesenchymal stem-like cells from a single primitive neuroectodermal tumor specimen
    CHILDS NERVOUS SYSTEM 29/12 :2229-2239,2013
  • Bilateral modified nasoseptal "rescue" flaps in the endoscopic endonasal transsphenoidal approach
    LARYNGOSCOPE 123/11 :2605-2609,2013
  • Isolation of Mesenchymal Stem-like Cells from a Pituitary Adenoma Specimen
    대한의생명과학회지 19/4 :295-302,2013
  • Temozolomide salvage chemotherapy for recurrent anaplastic oligodendroglioma and oligo-astrocytoma
    JOURNAL OF KOREAN NEUROSURGICAL SOCIETY 54/6 :489-495,2013
  • Study of freshly excised brain tissues using terahertz imaging
    BIOMEDICAL OPTICS EXPRESS 5/8 :2837-2842,2014
  • Role of the superior turbinate when performing endoscopic endonasal transsphenoidal approach
    FOLIA MORPHOLOGICA 73/1 :73-78,2014
  • Prognostic value of glioma cancer stem cell isolation in survival of primary glioblastoma patients
    STEM CELLS INTERNATIONAL 2014/0 :0-0,2014
  • Atypical location and clinical behavior of a subset of intracranial germ cell tumors in children younger than 3 years of age
    JOURNAL OF NEUROSURGERY-PEDIATRICS 14/4 :348-355,2014
  • Potential use of glioblastoma tumorsphere: Clinical credentialing
    ARCHIVES OF PHARMACAL RESEARCH 38/3 :402-407,2015
  • T2 - and T*2-weighted MRI of rat glioma using polysorbate-coated magnetic nanocrystals as a blood-pool contrast agent
    RSC ADVANCES 5/25 :19708-19714,2015
  • Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy
    NATURE MEDICINE 21/4 :395-400,2015
  • Primary diffuse leptomeningeal gliosarcoma
    Brain Tumor Reserach and Treatment 3/1 :34-38,2015
  • The Added Prognostic Value of Preoperative Dynamic Contrast-Enhanced MRI Histogram Analysis in Patients with Glioblastoma: Analysis of Overall and Progression-Free Survival
    AMERICAN JOURNAL OF NEURORADIOLOGY 36/12 :2235-2241,2015
  • Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway
    STEM CELLS 33/8 :2400-2415,2015
  • Pseudoprogression in glioblastoma patients: the impact of extent of resection
    JOURNAL OF NEURO-ONCOLOGY 126/3 :559-566,2016
  • Tumor mesenchymal stem-like cell as a prognostic marker in primary glioblastoma
    STEM CELLS INTERNATIONAL 2016/Arti :1-7,2016
  • PKCδ activated by c-MET enhances infiltration of human glioblastoma cells through NOTCH2 signaling
    ONCOTARGET 7/4 :4890-4902,2016
  • Strategies of mesenchymal invasion of patient-derived brain tumors: Microenvironmental adaptation.
    SCIENTIFIC REPORTS 25/6 :24912-24912,2016
  • Current and future perspectives in craniosynostosis.
    JOURNAL OF KOREAN NEUROSURGICAL SOCIETY 59/3 :247-249,2016
  • Failure of a patient-derived xenograft for brain tumor model prepared by implantation of tissue fragments
    CANCER CELL INTERNATIONAL 16/43 :1-6,2016
  • Isolation and characterization of tumorspheres from a recurrent pineoblastoma patient: Feasibility of a patient-derived xenograft.
    INTERNATIONAL JOURNAL OF ONCOLOGY 49/ :567-578,2016
  • Histopathological implications of ventricle wall 5-aminolevulinic acid-induced fluorescence in the absence of tumor involvement on magnetic resonance images
    ONCOLOGY REPORTS 36/2 :837-844,2016
  • A polyethylene glycol-based hydrogel as macroporous scaffold for tumorsphere formation of glioblastoma multiforme
    JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY 39/ :10-15,2016
  • Incremental Prognostic Value of ADC Histogram Analysis over MGMT Promoter Methylation Status in Patients with Glioblastoma
    RADIOLOGY 281/1 :175-184,2016
  • Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A)
    ONCOTARGET 7/40 :65,643-65,659,2016
  • Terahertz reflectometry imaging for low and high grade gliomas
    SCIENTIFIC REPORTS 6/36,040 :1-9,2016
  • Success of tumorsphere isolation from WHO grade IV gliomas does not correlate with the weight of fresh tumor specimens: an immunohistochemical characterization of tumorsphere differentiation
    CANCER CELL INTERNATIONAL 16/75 :1-7,2016
  • Hemangiopericytomas in the Central Nervous System: A Multicenter Study of Korean Cases with Validation of the Usage of STAT6 Immunohistochemistry for Diagnosis of Disease
    ANNALS OF SURGICAL ONCOLOGY 23/ :S954-S961,2016
  • Tumor-associated mesenchymal stem-like cells provide extracellular signaling cue for invasiveness of glioblastoma cells
    ONCOTARGET 8/1 :1,438-1,448,2017
  • Concurrent Chemoradiotherapy with Temozolomide Followed by Adjuvant Temozolomide for Newly Diagnosed Glioblastoma Patients: A Retrospective Multicenter Observation Study in Korea
    CANCER RESEARCH AND TREATMENT 49/1 :193-203,2017
  • Inhibition of glioblastoma tumorspheres by combined treatment with 2-deoxyglucose and metformin
    NEURO-ONCOLOGY 19/2 :197-207,2017
  • Primary central nervous system lymphoma and atypical glioblastoma: differentiation using the initial area under the curve derived from dynamic contrast-enhanced MR and the apparent diffusion coefficient
    EUROPEAN RADIOLOGY 27/4 :1,344-1,351,2017

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