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소속

  • 신경외과학교실

직위

  • 교수

연구실 위치

  • 의과대학 본관 510호

전화/팩스

  • 02) 2228-2155 /

학력사항

  • 1978 연세대학교 의학과 의학사
    1983 연세대학교 대학원 의학과 의학석사
    1989 연세대학교 대학원 의학과 의학박사

교육 및 연구 경력

  • 1990-1992 Univ. of Texas, Marine Biomedical Institute,연구원
    1996.3-2002.2 연세의대 신경외과 부교수
    2002.3- 연세의대 신경외과 교수
    2003-2005.2 연세대 의학도서관관장
    2011.3- 세브란스병원 뇌종양전문클리닉 팀장

기타 학술 관련 경력

  • 대한신경외과학회 정회원
    국제뇌하수체종양학회 정회원

연구,관심분야

  • 뇌하수체종양
    경동맥질환
    뇌종양

강의분야

  • 신경외과
    뇌혈관질환
    뇌종양학

논문

  • Emergency Endovascular Treatment of Internal Carotid Artery Injury During a Transsphenoidal Approach for a Pituitary Tumor -Case Report-
    YONSEI MEDICAL JOURNAL / :-,2002
  • Compressed spectral array를 이용한 뇌허혈 증상에 대한 뇌보호방법 정립에 관한 임상실험
    대한신경외과학회지(JOURNAL OF KOREAN NEUROSURGICAL SOCIETY) 32/4 :341-352,2002
  • Compressed spectral array 감시하의 쥐의 중뇌동맥 일시적 폐쇄로 유발된 국소적 뇌허혈에 대한 thiopental, propofol, dantrolene의 뇌보호효과의 비교
    대한신경외과학회지(JOURNAL OF KOREAN NEUROSURGICAL SOCIETY) 32/3 :239-245,2002
  • 급성 허혈성 뇌졸중 환자에서 내경동맥 협착의 특성
    대한신경과학회지(JournalOfTheKoreanNeurologicalAssociation) 21/2 :121-127,2003
  • 경동맥 절제술 후 재건에 사용된 복재정맥의 혈관구경 불일치를 극복하기 위한 Titanium Hemostatic Clip 봉합방법
    대한두경부종양학회지 20/2 :177-180,2004
  • Squash smear findings of spherical amyloid in pituitary prolactinoma: A case report
    ACTA CYTOLOGICA 48/3 :447-450,2004
  • 침습성 프로락틴 분비 뇌하수체 선종에서 Bromocriptine의 치료효과
    대한신경외과학회지(JOURNAL OF KOREAN NEUROSURGICAL SOCIETY) 37/4 :275-281,2005
  • Titanium hemostatic clip tailoring method to overcome vessel caliber discrepancy in interposition saphenous vein graft for carotid artery resection
    ACTA OTO-LARYNGOLOGICA 125/6 :638-641,2005
  • 감압 두개골 절제술을 시행 받은 공간 점유성 뇌경색 환자의 치료 성적과 예후 인자
    대한뇌혈관외과학회지(Korean Journal of Cerebrovascular Surgery) 7/1 :44-47,2005
  • 대동맥 죽상경화를 동반한 급성 뇌경색 환자의 임상적 특징
    대한뇌졸중학회지 7/2 :165-171,2005
  • 외상성 시신경병증의 시신경 감압술을 통한 치험례
    대한성형외과학회지(J Korean Soc Plast Reconstr Surg) 32/3 :389-392,2005
  • Cranial nerve palsies accompanying pituitary tumour
    JOURNAL OF CLINICAL NEUROSCIENCE 14/12 :1158-1162,2007
  • Navigation-assisted transsphenoidal deflation of a detachable balloon in the cavernous sinus after embolization of a direct carotid-cavernous fistula
    ACTA NEUROCHIRURGICA 149/ :207-212,2007
  • PDA-phone-based instant transmission of radiological images over a CDMA network by combining the PACS screen with a Bluetooth-interfaced local wireless link
    JOURNAL OF DIGITAL IMAGING 20/ :131-139,2007
  • Pituitary adenoma and concomitant Rathke's cleft cyst
    ACTA NEUROCHIRURGICA 149/ :1223-1228,2007
  • A multispecialist teleconsultation system using multiple unicasting
    TELEMEDICINE JOURNAL AND E-HEALTH 13/5 :565-571,2007
  • Embolisation of indirect carotid-cavernous sinus dural arterio-venous fistulae using the direct superior ophthalmic vein approach
    Acta Neurochirurgica 150/ :557-561,2008
  • How to overcome the limitations to determine the resection margin of pituitary tumours with low-field intra-operative MRI during trans-sphenoidal surgery: usefulness of Gadolinium-soaked cotton pledgets
    Acta Neurochirurgica 150/ :763-771,2008
  • 임상적 비기능성 뇌하수체 종양의 미세현미경적 가성피막의 제거
    대한두개저외과학회지(J Korean Skull Base Society) 1/1 :21-25,2008
  • 비기능성 뇌하수체 거대선종과 유사한 안장가로막수종증: 증례보고 및 문헌고찰
    대한두개저외과학회지(J Korean Skull Base Society) 2/2 :86-89,2008
  • TUMOR TISSUE IDENTIFICATION IN THE PSEUDOCAPSULE OF PITUITARY ADENOMA: SHOULD THE PSEUDOCAPSULE BE REMOVED FOR TOTAL RESECTION OF PITUITARY ADENOMA?
    Neurosurgery 64/3 :62-70,2009
  • Management strategies of intercavernous sinus bleeding during transsphenoidal surgery
    Acta Neurochirurgica 151/0 :803-803,2009
  • Late development of craniopharyngioma following surgery for Rathke's cleft cyst
    Clinical Neuropathology 28/3 :177-181,2009
  • Predicting Recurrence of Nonfunctioning Pituitary Adenomas
    Journal of clinical endocrinology and metabolism 94/ :4406-4413,2009
  • A new technique for dural suturing with fascia graft for cerbrospinal fluid leakage in transsphenoidal surgery
    Neurosurgery 65/1 :ONS65-ONS72,2009
  • Emergency endovascular Stent graft and coil placement for internal carotid artery injury during transsphenoidal surgery
    Surgical Neurology 72/ :741-746,2009
  • Management strategies of intercavernous sinus bleeding during transsphenoidal surgery
    Acta Neurochirurgica 151/7 :803-808,2009
  • Discrimination of prolactinoma from hyperprolactinemic non-functioning adenoma
    ENDOCRINE 37/ :140-147,2010
  • An endodermal cyst mimicking an intra-axial tumor in the medulla oblongata
    CHILDS NERVOUS SYSTEM 26/6 :853-856,2010
  • Surgical Treatment of Carotid Body Paragangliomas: Outcomes and Complications According to the Shamblin Classification
    Clinical And Experimental Otorhinolaryngology 3/2 :91-95,2010
  • A case of fugitive acromegaly, initially presented as invasive prolactinoma
    ENDOCRINE 38/1 :1-5,2010
  • Topographic variations of the optic chiasm and the foramen diaphragma sellae
    SURGICAL AND RADIOLOGIC ANATOMY 32/7 :653-657,2010
  • 비기능성 뇌하수체 선종 환자에게서 뇌하수체 기능 저하와 자기공명영상검사 소견과의 상관 관계
    Journal Of The Korean Society Of Endocrinology(대한내분비학회지) 25/4 :310-315,2010
  • Prevention of Cerebrospinal Fluid Rhinorrhea After Transsphenoidal Surgery by Collagen Fleece Coated With Fibrin Sealant Without Autologous Tissue Graft or Postoperative Lumbar Drainage
    NEUROSURGERY 68/3 :130-137,2011
  • Application of intraoperative indocyanine green videoangiography to brain tumor surgery
    ACTA NEUROCHIRURGICA 153/7 :1487-1495,2011
  • Technique and outcome of endoscopy-assisted microscopic extended transsphenoidal surgery for suprasellar craniopharyngiomas
    JOURNAL OF NEUROSURGERY 114/5 :1338-1349,2011
  • Clinical management and outcome of 36 invasive prolactinomas treated with dopamine agonist
    JOURNAL OF NEURO-ONCOLOGY 104/1 :195-204,2011
  • Intraoperative multiple-staged resection and tumor tissue identification using frozen sections provide the best result for the accurate localization and complete resection of tumors in Cushing's disease
    ENDOCRINE 40/3 :452-461,2011
  • Sudden asystole due to trigeminocardiac reflex during transsphenoidal surgery for pituitary tumor
    WORLD NEUROSURGERY 76/5 :477e11-477e15,2011
  • Recurred cerebellopontine angle haemangiopericytoma 5 years after stereotactic radiosurgery
    CLINICAL NEUROLOGY AND NEUROSURGERY 113/10 :931-933,2011
  • TSH 분비 뇌하수체 선종 환자들의 임상적, 생화학적 특징과 치료
    Korean J Med 80/1 :47-55,2011
  • Predicting Long-term Remission by Measuring Immediate Postoperative Growth Hormone Levels and Oral Glucose Tolerance Test in Acromegaly
    NEUROSURGERY 70/ :1106-1112,2012
  • 수술 전 잘못 진단되었던 뇌하수체 선종과 터키안결절 뇌수막종 환자들의 영상학적 소견과 임상 양상에 관한 분석
    대한뇌종양학회지 11/1 :33-37,2012
  • Coexistence of intracranial aneurysm in 800 patients with surgically confirmed pituitary adenoma
    JOURNAL OF NEUROSURGERY 116/ :942-947,2012
  • Optimal Surgical Approaches for Rathke Cleft Cyst With Consideration of Endocrine Function
    NEUROSURGERY 70/ :250-257,2012
  • Clinical results of the superior parieto-occipital transcortical approach for intraventricular meningiomas in the trigone of lateral ventricle: a report of 24 cases
    대한뇌종양학회지 11/2 :108-113,2012
  • Surgical and Endocrinological Outcomes in the Treatment of Growth Hormone-Secreting Pituitary Adenomas with a Shift in the Surgical Paradigm
    NEUROSURGERY 71/2 Supp :ons192-ons203,2012
  • 경접형동 접근에 의한 뇌하수체 선종 제거술 후 발생한 지연성 저나트륨혈증 : 임상 연구
    대한뇌종양학회지 11/2 :96-101,2012
  • Isolation of glioma cancer stem cells in relation to histological grades in glioma specimens.
    CHILDS NERVOUS SYSTEM 29/2 :217-229,2013
  • Changes in the biological characteristics of glioma cancer stem cells after serial in vivo subtransplantation.
    CHILDS NERVOUS SYSTEM 29/1 :55-64,2013
  • Existence of glioma stroma mesenchymal stemlike cells in Korean glioma specimens
    CHILDS NERVOUS SYSTEM 29/4 :549-563,2013
  • Transventricular Endoscopic Fenestration of Intrasellar Arachnoid Cyst
    NEUROSURGERY 72/4 :520-528,2013
  • Increased in vivo angiogenic effect of glioma stromal mesenchymal stem-like cells on glioma cancer stem cells from patients with glioblastoma
    INTERNATIONAL JOURNAL OF ONCOLOGY 42/5 :1754-1762,2013
  • Isolation of mesenchymal stem-like cells in meningioma specimens
    INTERNATIONAL JOURNAL OF ONCOLOGY 43/4 :1260-1268,2013
  • Angiographically documented cerebral vasospasm following transsphenoidal surgery for pituitary tumors
    PITUITARY 16/2 :260-269,2013
  • Application of low-field intraoperative magnetic resonance imaging in transsphenoidal surgery for pituitary adenomas: technical points to improve the visibility of the tumor resection margin
    ACTA NEUROCHIRURGICA 155/3 :485-493,2013
  • Isolation of tumor spheres and mesenchymal stem-like cells from a single primitive neuroectodermal tumor specimen
    CHILDS NERVOUS SYSTEM 29/12 :2229-2239,2013
  • Clinical Use of Diffusion Tensor Image-Merged Functional Neuronavigation for Brain Tumor Surgeries: Review of Preoperative, Intraoperative, and Postoperative Data for 123 Cases
    YONSEI MEDICAL JOURNAL 55/5 :1303-1309,2014
  • Clinical predictors of GH deficiency in surgically cured acromegalic patients
    EUROPEAN JOURNAL OF ENDOCRINOLOGY 171/3 :379-387,2014
  • Evaluation of MRI Criteria for Cavernous Sinus Invasion in Pituitary Macroadenoma
    JOURNAL OF NEUROIMAGING 24/5 :498-503,2014
  • Prognostic value of glioma cancer stem cell isolation in survival of primary glioblastoma patients
    STEM CELLS INTERNATIONAL 2014/0 :0-0,2014
  • Potential use of glioblastoma tumorsphere: Clinical credentialing
    ARCHIVES OF PHARMACAL RESEARCH 38/3 :402-407,2015
  • Direct Suture Technique of Normal Gland Edge on the Incised Dura Margin to Repair the Intraoperative Cerebrospinal Fluid Leakage From the Arachnoid Recess During Transsphenoidal Pituitary Tumor Surgery.
    NEUROSURGERY 11/1 :26-31,2015
  • Extracapsular en bloc resection in pituitary adenoma surgery
    PITUITARY 18/3 :397-404,2015
  • Rapid Reticulin Fiber Staining Method is Helpful for the Diagnosis of Pituitary Adenoma in Frozen Section
    ENDOCRINE PATHOLOGY 26/2 :178-184,2015
  • Differentiation between Cystic Pituitary Adenomas and Rathke Cleft Cysts: A Diagnostic Model Using MRI
    AMERICAN JOURNAL OF NEURORADIOLOGY 36/10 :1866-1873,2015
  • Use of optical coherence tomography to predict visual outcome in parachiasmal meningioma
    JOURNAL OF NEUROSURGERY 123/6 :1489-1499,2015
  • Pediatric giant cell tumor of the tendon sheath of the craniocervical junction involving the occipital condyle
    CHILDS NERVOUS SYSTEM 32/1 :175-179,2016
  • Pseudoprogression in glioblastoma patients: the impact of extent of resection
    JOURNAL OF NEURO-ONCOLOGY 126/3 :559-566,2016
  • Tumor mesenchymal stem-like cell as a prognostic marker in primary glioblastoma
    STEM CELLS INTERNATIONAL 2016/Arti :1-7,2016
  • Failure of a patient-derived xenograft for brain tumor model prepared by implantation of tissue fragments
    CANCER CELL INTERNATIONAL 16/43 :1-6,2016
  • Isolation and characterization of tumorspheres from a recurrent pineoblastoma patient: Feasibility of a patient-derived xenograft.
    INTERNATIONAL JOURNAL OF ONCOLOGY 49/ :567-578,2016
  • Histopathological implications of ventricle wall 5-aminolevulinic acid-induced fluorescence in the absence of tumor involvement on magnetic resonance images
    ONCOLOGY REPORTS 36/2 :837-844,2016
  • Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A)
    ONCOTARGET 7/40 :65,643-65,659,2016
  • No differences in metabolic outcomes between nadir GH 0.4 and 1.0 ng/mL during OGTT in surgically cured acromegalic patients (observational study)
    MEDICINE 95/24 :e3,808-,2016
  • Predictive model for recovery of visual field after surgery of pituitary adenoma
    JOURNAL OF NEURO-ONCOLOGY 130/1 :155-164,2016
  • Success of tumorsphere isolation from WHO grade IV gliomas does not correlate with the weight of fresh tumor specimens: an immunohistochemical characterization of tumorsphere differentiation
    CANCER CELL INTERNATIONAL 16/75 :1-7,2016
  • Snare technique for the remodeling of the redundant arachnoid pouch to prevent cerebrospinal fluid rhinorrhea and hematoma collection during transsphenoidal surgery for suprasellar-extended pituitary tumors
    JOURNAL OF NEUROSURGERY 125/6 :1,443-1,450,2016
  • Inhibition of glioblastoma tumorspheres by combined treatment with 2-deoxyglucose and metformin
    NEURO-ONCOLOGY 19/2 :197-207,2017

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