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소속

  • 신경과학교실

보직

  • 과장(科長)

직위

  • 교수

연구실 위치

  • 강남세브란스병원

전화/팩스

  • 02) 2019-2370 /

학력사항

  • 석사 연세대학교 의과학: 1986-1988
    박사 연세대학교 의과학: 1989-1992

교육 및 연구 경력

  • 전임강사 연세대학교 의과대학: 1988-1991
    조교수 연세대학교 의과대학: 1991-1997
    영국 런던 퀸스퀘어(Queen Square) 국립병원 연수:1992-1994
    부교수 연세대학교 의과대학: 1997-2002
    교 수 연세대학교 의과대학: 2002-

기타 학술 관련 경력

  • 아시아 태평양 파킨슨병 학회 사무총장: 2001-2003
    대한 파킨슨병 및 이상운동 질환 학회 회장(초대,2대): 2006년-2009년

    [수상내역]
    * 1998년 : 제5회 세계 파킨슨 병 학회 우수 논문 상
    * 2001년 : 동아일보 선정 뇌 비혈관 질환분야 베스트중견의사
    * 2002년 : 연세대학교 연구 업적 우수 교수 상
    * 2004년 동아일보 선정 뇌비혈관 질환분야 베스트 닥터
    * 2007년 : 제 11회 세계 파킨슨 병 학회; 우수 논문 상
    * 2008년 : 대한 파킨슨병 및 이상운동질환학회: 제 1회 BI-KMDS 학술상
    * 2008년 : 연세의대 연구업적 우수상

연구,관심분야

  • 파킨슨병, 이상운동 질환

강의분야

  • 파킨슨병 및 운동장애

논문

  • Lee MS*, Lee SA, Heo JH, Cho IS. A patient with a resting tremor following a lacunar infarction at the borderline between that the thalamus and internal capsule. Movement Disorders 1993;8:244-246.
  • Lee MS, Marsden CD*. Movement disorders following lesions of the thalamus or subthalamic region. A review. Movement Disorders 1994;9:493-507.
  • Lee MS, Rinne JO, Ceballos-Bauman A, Thompson PD, Marsden CD*. Dystonia after head trauma. Neurology 1994;44:1374-1378.
  • Lee MS, Marsden CD*. Neurological sequelae following carbon monoxide poisoning. Clinical course and outcome according to the clinical types and brain computerized tomography findings. Movement Disorders 1994;9:550-558.
  • Rinne JO, Lee MS, Thompson PD, Marsden CD*. Corticobasal degeneration. Clinical study of 36 cases. Brain 1994;117:1183-1196.
  • Lee MS*, Choi YC, Heo JH, Choi IS. "Drop attacks" with stiffening of the right leg associated with posterior fossa arachnoid cyst. Movement Disorders 1994;9:377-378.
  • Lee MS*, Choi YC, Lee SB, Lee SH. Sleep related periodic leg movements associated with spinal cord lesions. Movement Disorders 1996;11:719-722.
  • Lee MS*, Lee SB, Kim WC. Spasmodic dysphonia associated with a ventrolateral putaminal lesion. Neurology 1996;47:827-828.
  • Lee MS*, Lyoo CH, Kim WC. Periodic bursts of rhythmic dyskinesia associated with spinal anesthesia. Movement Disorders 1997;12:816-817.
  • Lee MS*, Kim WC. Intracranial hemorrhage associated with idiopathic thrombocytopenic purpura. Neurology 1998; 50:1160-1163.
  • Lee MS*, Kim YD, Lim JT, Lyoo CH. Abrupt onset of transient pseudochoreoathetosis associated with proprioceptive sensory loss as a result of thalamic infarction. Movement Disorders 1998;13:184-186.
  • Gouw LG, Castaneda MA, McKenna CK, Digre KB, Pulst SM, Lee MS, Gomez C, Fischbeck K, Gagnon D, Storey E, Bird T, Jeri FR, Ptacek LJ. Analysis of the dynamic mutation in the SCA7 gene shows marked parental effects on CAG repeat transmission. Human Molecular Genetics 1998;7:525-532.
  • Lee MS*, Kim YD, Im JH, Kim HJ, Rinne JO, Bhatia KP. 123I-IPT brain SPECT in essential tremor and Parkinson's disease. Neurology 1999;52:1422-1426.
  • Lee MS*, Kim WC, Lyoo CH, Lee HJ. Reciprocal inhibition between the forearm muscles in patients with paroxysmal kinesigenic dyskinesia. J Neurol Sci 1999;168:57-61.
  • Lee MS*, Kim YD, Lyoo CH. Oculogyric crisis as an initial manifestation of Wilson's disease. Neurology 1999;52:1714-1715.
  • Lee MS*, Kim YD, Kim WC, Lyoo CH. Slow rhythmic dyskinesia of the shoulder. Movement Disorders 1999;14:1049-1051.
  • Stenvanin G, David G, Durr A, Giunt P, Benomar A, Abada-Bedib M, Lee MS, Agid Y, Brice A. Multiple origins of the spinocerebellar ataxia 7 (SCA7) mutation revealed by linkage disequilibrium studies with closely flanking markers, including an iatrogenic polymorphism (G3145 TG/ A 3145 TG). Eur J Hum Gent 1999;7:889-896.
  • Jin DK, Oh MR, Song SM, Koh MH, Kim GM, Lee WY, Chung CS, Lee KH, Im JH, Lee MJ, Kim JW, Lee MS. Frequency of spinocerebelar ataxia type 1, 2, 3, 6, 7 and dentatorubral pallidoluysian atrophy mutations in Korean patients with spinocerebellar ataxia. J Neurol 1999;246:207-210.
  • 뇌 자기공명영상에서 뇌간과 소뇌 계측을 이용한 다계통위축증과 파킨슨병의 감별 진단
    대한신경과학회지(JournalOfTheKoreanNeurologicalAssociation) 22/5 :478-484,2004
  • 시상하핵 뇌심부자극이 파킨슨병 환자들의 발성과 조음에 미치는 영향
    대한신경과학회지(JournalOfTheKoreanNeurologicalAssociation) 22/5 :472-477,2004
  • 파킨슨병 환자에서 전극선의 부분 손상으로 인한 시상하핵 자극 효과 소실
    대한신경과학회지(JournalOfTheKoreanNeurologicalAssociation) 23/6 :820-822,2005
  • Wearing-off 현상을 경험하는 파킨슨병 환자에서 엔타카폰의 효과 및 안정성: 다기관 무작위 위약비교 이중맹검 연구
    JOURNAL OF THE KOREAN NEUROLOGICAL ASSOCIATION 23/2 :206-214,2005
  • "Off" gait freezing and temporal discrimination threshold in patients with Parkinson disease
    NEUROLOGY 64/ :670-674,2005
  • Corticospinal disinhibition in paroxysmal kinesigenic dyskinesia
    CLINICAL NEUROPHYSIOLOGY 117/ :57-60,2006
  • 파킨슨병과 다계통위축증 감별 진단에 정량적 18-fluorodeoxyglucose PET의 유용성
    대한신경과학회지(JournalOfTheKoreanNeurologicalAssociation) 24/1 :31-37,2006
  • 젊은 나이에 산발성 파킨슨병이 생긴 한국인 환자의 Parkin 유전자 변이
    대한신경과학회지(JournalOfTheKoreanNeurologicalAssociation) 24/1 :26-30,2006
  • 파킨슨병에 대한 시상하핵 심부뇌자극술
    대한신경과학회지(JournalOfTheKoreanNeurologicalAssociation) 24/3 :191-203,2006
  • Abnormal temporal discrimination threshold in patients with multiple system atrophy
    MOVEMENT DISORDERS 22/4 :556-559,2007
  • Moyamoya disease presenting with paroxysmal exercise-induced dyskinesia
    PARKINSONISM & RELATED DISORDERS 13/ :446-448,2007
  • Different cerebral cortical areas influence the effect of subthalamic nucleus stimulation on Parkinsonian motor deficits and freezing of gait
    MOVEMENT DISORDERS 22/15 :2176-2182,2007
  • Use of the putamen/caudate volume ratio for early differentiation between Parkinsonian variant of multiple system atrophy and Parkinson disease
    Journal of Clinical Neurology 3/ :79-81,2007
  • Effects of disease duration on the clinical features and brain glucose metabolism in patients with mixed type multiple system atrophy
    Brain 131/ :438-446,2008
  • Anticholinergic-responsive gait freezing in a patient with pantothenate kinase-associated neurodegeneration
    Movement Disorders 23/ :283-284,2008
  • 전형적, 비전형적 임상 양상을 보인 Neurodegeneration With Brain Iron Accumulation 환자
    대한신경과학회지(Journal Of The Korean Neurological Association) 26/3 :243-246,2008
  • Drug-induced and psychogenic resting suprahyoid neck and tongue tremors
    Movement Disorders 23/ :746-748,2008
  • 조기 발현 파킨슨병 환자에서 SCA2, SCA3과SCA17 유전자 내의 삼염기 반복수 변화
    대한신경과학회지(Journal Of The Korean Neurological Association) 26/1 :23-27,2008
  • 파킨슨병 환자들에서 넘어짐과 신체 손상
    대한 파킨슨병 및 이상운동질환학회 1/1 :13-18,2008
  • Relationship between the striatal and cerebellar glucose metabolism and the response to levodopa treatment in patients with multiple system atrophy
    대한 파킨슨병 및 이상운동질환학회 1/1 :26-32,2008
  • Analysis of PARK genes in a Korean cohort of early-onset Parkinson disease
    Neurogenetics 9/4 :263-269,2008
  • Loss of cholinergic neurons in the pedunculopontine nucleus in Parkinson's disease is related to disability of the patients
    Parkinsonism & Related Disorders 14/7 :553-557,2008
  • 치료받지 않은 특발성 파킨슨병 환자들의 혈장 호모시스테인 농도와 C677T MTHFR 유전자형의 관계
    Journal of Movement Disorders 1/2 :71-74,2008
  • 유전자 검사로 확인된 제 8형 척수소뇌성실조증 1예
    Journal of Movement Disorders 1/2 :90-92,2008
  • Functional peak dose dyskinesia in patients with Parkinson's disease
    Parkinsonism & Related Disorders 15/6 :475-476,2009
  • Oculogyric crisis associated with disulfiram-induced pallidonigral lesion
    Journal of Movement Disorders 2/ :48-49,2009
  • Psychogenic paroxysmal dyskinesia: The role of placebo in the diagnosis and management
    Movement Disorders 24/8 :1244-1245,2009
  • Scoliosis in Patients with Parkinson's Disease
    Journal Of Clinical Neurology 5/2 :91-94,2009
  • giant somatosensory evoked potential in a patient with shaking TIA
    Movement Disorders 24/15 :2301-2303,2009
  • Topographical distribution of cerebral cortical thinning in patients with mild Parkinson's disease without dementia
    Movement Disorders 25/4 :496-499,2010
  • Movement disorders associated with moyamoya disease: A report of 4 new cases and a review of literatures
    Movement Disorders 25/10 :1482-1486,2010
  • Primary Progressive Freezing Gait in a Patient with CO-Induced Parkinsonism
    Movement Disorders 25/10 :1513-1515,2010
  • Cerebral glucose metabolism of Parkinson's disease patients with mild cognitive impairment
    European Neurology 64/2 :65-73,2010
  • Levodopa responsive hemidystonia associated with contralateral nigral lesion
    Journal of Neurology 257/5 :856-857,2010
  • Bilateral ballism after herpes encephalitis with thalamic lesion
    Parkinsonism & Related Disorders 16/4 :303-304,2010
  • Impaired finger dexterity in patients with parkinson's disease correlates with discriminative cutaneous sensory dysfunction
    Movement Disorders 25/15 :2531-2535,2010
  • Posttraumatic Hemidystonia Treated with Unilateral Globus Pallidus Interna Stimulation: Long-Term Follow-up and Radiologic Features
    Neuromodulation 13/ :261-264,2010
  • Imaging Evidence of Nigral Damage in Dystonia Secondary to Disulfiram Intoxication
    MOVEMENT DISORDERS 26/4 :763-764,2011
  • Sonographic abnormalities in idiopathic restless legs syndrome (RLS) and RLS in Parkinson's disease
    PARKINSONISM & RELATED DISORDERS 17/3 :201-203,2011
  • The effect of age on motor deficits and cerebral glucose metabolism of Parkinson's disease
    ACTA NEUROLOGICA SCANDINAVICA 124/3 :196-201,2011
  • Rhabdomyolysis induced by severe levodopa induced dyskinesia in a patient with Parkinson's disease
    JOURNAL OF NEUROLOGY 258/0 :1893-1894,2011
  • Mesencephalic midline change on transcranial sonography in early Parkinson's disease patients with depression
    JOURNAL OF THE NEUROLOGICAL SCIENCES 310/1-2 :50-52,2011
  • Cerebral cortical areas in which thickness correlates with severity of motor deficits of Parkinson's disease
    JOURNAL OF NEUROLOGY 258/10 :1871-1876,2011
  • A patient with genetically confirmed myoclonus-dystonia responded to anticholinergic treatment and improved spontaneously
    JOURNAL OF CLINICAL NEUROLOGY 7/4 :231-232,2011
  • Neuroleptic Malignant Syndrome in a Patient with Corticobasal Degeneration
    Journal of Movement Disorders 4/ :73-74,2011
  • Association of mutations in the glucocerebrosidase gene with Parkinson disease in a Korean population.
    NEUROSCIENCE LETTERS 514/1 :12-15,2012
  • Striatal dopamine loss and discriminative sensory dysfunction in Parkinson's disease
    ACTA NEUROLOGICA SCANDINAVICA 126/5 :344-349,2012
  • Factors related to outcomes of subthalamic deep brain stimulation in Parkinson’s disease
    JOURNAL OF KOREAN NEUROSURGICAL SOCIETY 54/2 :118-124,2013
  • Cognitive dysfunction associated with falls in progressive supranuclear palsy
    GAIT & POSTURE 40/4 :605-609,2014
  • Expansion of the clinicopathological and mutational spectrum of Perry syndrome
    PARKINSONISM & RELATED DISORDERS 20/4 :388-393,2014
  • Kinematic Analysis in Patients with Parkinson's Disease and SWEDD
    JOURNAL OF PARKINSONS DISEASE 4/3 :421-430,2014
  • Neuroimaging studies and whole exome sequencing of PLA2G6-associated neurodegeneration in a family with intrafamilial phenotypic heterogeneity
    PARKINSONISM & RELATED DISORDERS 21/4 :402-406,2015
  • Current Status of Huntington's Disease in Korea: A Nationwide Survey and National Registry Analysis
    Journal of Movement Disorders 8/1 :14-20,2015
  • 대뇌피질 대사저하가 관찰된안구간대경련-근간대경련증후군
    대한신경과학회지 33/2 :103-105,2015
  • Impact of regional striatal dopaminergic function on kinematic parameters of Parkinson’s disease
    JOURNAL OF NEURAL TRANSMISSION 122/5 :669-677,2015
  • Parkinsonism and Dementia Associated with Giant Virchow-Robin Spaces
    Journal of Movement Disorders 8/2 :106-107,2015
  • Feasibility of Computed Tomography-Guided Methods for Spatial Normalization of Dopamine Transporter Positron Emission Tomography Image
    PLOS ONE 10/7 :e0132585-,2015
  • Overlap of autism spectrum disorder and glucose transporter 1 deficiency syndrome associated with a heterozygous deletion at the 1p34.2 region
    JOURNAL OF THE NEUROLOGICAL SCIENCES -/356 :212-214,2015
  • [(18)F] FP-CIT PET study in parkinsonian patients with leukoaraiosis.
    PARKINSONISM & RELATED DISORDERS 21/7 :704-708,2015
  • Tau Accumulation in Primary Motor Cortex of Variant Alzheimer's Disease with Spastic Paraparesis
    JOURNAL OF ALZHEIMERS DISEASE 51/3 :671-675,2016
  • Clinical Heterogeneity of Atypical Pantothenate Kinase-Associated Neurodegeneration in Koreans
    Journal of Movement Disorders 9/1 :20-27,2016
  • Tau PET in Alzheimer disease and mild cognitive impairment
    NEUROLOGY 87/4 :375-383,2016
  • In vivo cortical spreading pattern of tau and amyloid in the Alzheimer disease spectrum
    ANNALS OF NEUROLOGY 80/2 :247-258,2016
  • Delayed iron deposit and atrophy of the putamen in a case with osmotic demyelination syndrome
    JOURNAL OF THE NEUROLOGICAL SCIENCES 369/ :131-133,2016
  • Re-emergent Tremor Without Rest Tremor After Lenticular Infarctions
    Movement Disorders Clinical Practice -/- :96-97,2016
  • Impact of prolonged temporal discrimination threshold on finger movements of Parkinson’s disease.
    PLOS ONE 11/11 :e0167034-,2016
  • Subcortical 18F-AV-1451 Binding Patterns in Progressive Supranuclear Palsy
    MOVEMENT DISORDERS 32/1 :134-140,2017
  • 18F-AV-1451 Binds to Putamen in Multiple System Atrophy
    MOVEMENT DISORDERS 32/1 :171-173,2017
  • Clinical features indicating reduced nigrostriatal dopaminergic innervation in patients with drug-induced parkinsonism.
    Journal of Movement Disorders 10/1 :35-39,2017
  • Excessive tau accumulation in the parieto-occipital cortex characterizes early-onset Alzheimer's disease
    NEUROBIOLOGY OF AGING 53/ :103-111,2017
  • Paroxysmal freezing of gait in a patient with mesial frontal transient ischemic attacks
    BMC NEUROLOGY 17/ :122-122,2017
  • Parkinsonian Patients with Striatal Cribriform State Present Rapidly Progressive Axial Parkinsonism
    EUROPEAN NEUROLOGY 78/ :119-124,2017
  • Radiological Findings of Two Sisters with Aceruloplasminemia Presenting with Chorea
    CLINICAL NEURORADIOLOGY 27/ :385-388,2017
  • 18F-AV-1451 binds to motor-related subcortical gray and white matter in corticobasal syndrome
    NEUROLOGY 89/11 :1,170-1,178,2017

저서

  • Lee MS, C D Marsden. Drop attacks. Clinical Disorders of Balance, Posture and Gait. Eds. Bronstein A M, Brandt T, Wollacott M. Arnold, London, 1996; pp 177-187.
  • Lee MS, Marsden CD*. Drop attacks. Advances in Neurology, vol 67, Eds. Hallett M, Luder HO, Marsden CD, Raven Press, New York. 1995; pp 41-52.
  • Rinne JO, Lee MS, Neuroacanthocytosis. Parkinson's Disease and Movement Disorders. eds Jankovic J and Tolosa E, 4th ed. pp576-583. Lippincott Williams and Wilkins, Philadelphia
  • 4) Bhatia KP, Lee MS, Rinne JO, Revesz T, Scaravilli F, Davies L, Marsden CD. Corticobasal degeneration look-alikes. Advances in Neurology, vol 82, Eds. Litvan I, Goetz CG, Lang AE, Raven Press, New York. 2000; pp 169-182.
  • 번역서
  • 이명식. 운동장애, 최신신경학 김진수, 최경규, 이명식 (공저), 과학서적 쎈타. 1999: pp 352-371
  • Botulinum Toxin Literature Digest. 2007, Vol 1, pp 8-46. 임상내과,

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