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소속

  • 병리학교실

보직

  • 강남 세브란스 병리과장

직위

  • 교수

연구실 위치

  • 강남세브란스병원 본관3동 4층

전화/팩스

  • 02) 2019-3543 /

학력사항

  • 연세대학교 의학과 학사(1987)
    연세대학교 의학과 석사(1990)
    연세대학교 의학과 병리학 박사(1996)

교육 및 연구 경력

  • 1996.-1997. 연세원주의대 병리학교실 전임강사
    1997.-1998. 연세원주의대 병리학교실 조교수
    1998.-2002. 연세의대 병리학교실 조교수
    1999.-2000. Renal division of UPENN(University of Pennsylvania) visiting fellow
    2000.-2001. Cytology division of Pathology dep
    2002.-2008.2 연세의대 병리학교실 부교수
    2008.3~ 현재 연세의대 병리학교실 교수
    2008.3~ 현재 연세의대 강남세브란스병원 병리학과 과장
    2011.12~ 현재 강남)유전자은행장

기타 학술 관련 경력

  • 대한 병리학회 회원
    대한 병리학회-편집위원회 위원장
    대한 세포병리학회-편집위원회 위원장
    대한 신장학회 회원
    대한 이식학회 회원
    대한 갑상선학회 회원
    American society of nephrology-member
    USCAP-member
    내분비 병리연구회 감사
    ASC-member
    IAC-member

연구,관심분야

  • 당뇨병성 신증(diabetic nephropathy)
    갑상선암(papillary carcinoma)
    세포병리(cytology)
    내분비병리

강의분야

  • 신장 질환의 병리,
    내분비 병리,
    세포 병리

논문

  • Therapy with antisense TGF-b1 oligodeoxynucleotides reduces kidney weight and matrix mRNAs in diabetic mice
    COORDINATION CHEMISTRY REVIEWS 278/0 :628-634,2000
  • Alterations in extracellular matrix components in transplant glomerulopathy
    VIRCHOWS ARCHIV 437/1 :69-73,2000
  • Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice.
    Proc Natl Acad Sci U S A 97/14 :8015-8020,2000
  • A case of membranoproliferative glomerulonephritis associated with a
    YONSEI MEDICAL JOURNAL 0/0 :0-0,2000
  • The key role of the transforming growth factor-beta system in the pathogenesis of diabetic nephropathy
    Ren Fail 23/0 :471-481,2001
  • Leptin stimulates type I collagen production in db/db mesangial cells: Glucose uptake and TGF-beta type II receptor expression
    KIDNEY INTERNATIONAL 59/4 :1315-1323,2001
  • Granzyme B and TIA-1 expression in chronic and acute on chronic renal allograft rejection.
    YONSEI MEDICAL JOURNAL 42/3 :285-290,2001
  • Acinic cell carcinoma of the lacrimal gland with intracranial extension: a case
    Ophthal Plast Reconstr Surg 0/0 :0-0,2001
  • Increased glomerular and tubular expression of transforming growth factor-beta1, its type II receptor, and activation of the Smad signaling pathway in the db/db mouse.
    AMERICAN JOURNAL OF PATHOLOGY 158/5 :1653-1663,2001
  • Tic convulsif caused by cerebellopontine angle schwannoma.
    YONSEI MEDICAL JOURNAL 0/0 :0-0,2001
  • Inhibiting albumin glycation in vivo ameliorates glomerular overexpression of TGF-beta1.
    Kidney Int 61/6 :2025-2032,2002
  • Diffuse glomerular basement membrane lamellation in post-transplant IgA nephropathy.
    YONSEI MEDICAL JOURNAL 0/0 :0-0,2002
  • Smad pathway is activated in the diabetic mouse kidney and Smad3 mediatesTGF-beta-induced fibronectin in mesangial cells.
    INTERNATIONAL GEOLOGY REVIEW 0/0 :0-0,2002
  • Metastasis of primitive neuroectodermal tumor to the breast
    JOURNAL OF CLINICAL ULTRASOUND 30/6 :374-377,2002
  • Delayed treatment with lithospermate B attenuates experimental diabetic renal injury
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 14/ :709-720,2003
  • Histologic factors associated with nephrotic-range proteinuria in recurrent IGA nephropathy.
    TRANSPLANTATION PROCEEDINGS 35/1 :291-291,2003
  • The effect of supraclavicular lymph node irradiation upon the thyroid gland in the post-operative breast carcinoma patients.
    YONSEI MEDICAL JOURNAL 44/5 :828-835,2003
  • Nuclear factor kappa B activation in glomeruli of posttransplant IgA nephropathy using southwestern histochemistry.
    TRANSPLANTATION PROCEEDINGS 35/1 :179-180,2003
  • Reversibility of established diabetic glomerulopathy by anti-TGF-beta antibodies in db/db mice
    Biochem Biophys Res Commun 300/1 :16-22,2003
  • EXPRESSION OF ESTROGEN RECEPTOR-β IN NORMAL MAMMARY AND TUMOR TISSUES IS IT PROTECTIVE IN BREAST CARCINOGENESIS?
    BREAST CANCER RESEARCH AND TREATMENT 80/1 :79-85,2003
  • Polyomavirus nephropathy in renal transplantation: a clinico-pathological study.
    Transpl Int 16/9 :671-675,2003
  • Expression of down stream molecules of RET (p-ERK, p-p38 MAPK, p-JNK and p-AKT) in papillary thyroid carcinomas.
    YONSEI MEDICAL JOURNAL 45/0 :306-313,2004
  • 감시림프절 전이 양성인 조기유방암 환자의 비감시림프절 전이의 예측
    한국유방암학회지(Journal Of Korean Breast Cancer Society) 7/4 :268-274,2004
  • 갑상선의 Warthin 모양 종양 1예
    대한두경부종양학회지 20/1 :33-36,2004
  • 막성 사구체신념을 동반한 Sjogren 증후군 1예
    The Korean Journal of Nephrology 23/6 :982-,2004
  • 사람의 제2형 당뇨병성 신증의 신조직내 TGF-β-inducible Gene-h3의 발현과 유용성-면역조직화학적 분석-
    The Korean Journal of Nephrology 23/4 :559-566,2004
  • 원발성 장 림프관 확장증 1례
    대한소아소화기영양학회지(Korean Journal of Pediatric Gastroenterology Nutrition) 7/2 :253-259,2004
  • 유두상 갑상선 암의 큰 세포 변이 (Tall Cell Variant)
    대한두경부종양학회지 20/2 :123-127,2004
  • 유두상 갑상선암의 원주형 변이 2예
    대한내분비외과학회지 4/2 :119-132,2004
  • 유방암 환자의 수술 중 Rapid Cytokeratin 면역화학 염색법을 이용한 감시림프절의 평가
    한국유방암학회지(Journal Of Korean Breast Cancer Society) 7/3 :154-159,2004
  • 출혈을 동반한 대여포성 유두상 갑상선 암종 -1예 보고-
    대한세포병리학회지(Korean Journal Of Cytopathology) 15/1 :60-64,2004
  • 폐경된 유방암 환자에서 Tamoxifen 사용후 발생한 자궁근종에서 Estrogen Receptor Alpha, beta, Progesterone Receptor 발현의 차이
    대한폐경학회지 10/1 :50-58,2004
  • 하시모토 갑상선염을 주소로 내원한 노인에서 발생한 갑상선 MALT 림프종(MALToma)1예
    임상노인의학회지 5/2 :239-245,2004
  • Expression of laminin-5 with amniotic membrane transplantation in excimer laser ablated rat corneas
    JOURNAL OF CATARACT AND REFRACTIVE SURGERY 30/10 :2192-2199,2004
  • Suppression of colorectal cancer liver metastasis and extension of survival by expression of apolipoprotein(a) kringles
    CANCER RESEARCH 64/19 :7092-7098,2004
  • 갑상선 선지방종 1예
    대한내분비외과학회지 4/1 :51-54,2004
  • Osteopontin expression and microvascular injury in cyclosporine nephrotoxicity
    PEDIATRIC NEPHROLOGY 19/ :288-294,2004
  • Papillary thyroid carcinoma associated with familial adenomatous polyposis: Molecular analysis of pathogenesis in a family and review of the literature
    ENDOCRINE JOURNAL 51/3 :317-323,2004
  • Expression of human apolipoprotein(a) kringles in colon cancer cells suppresses angiogenesis-dependent tumor growth and peritoneal dissemination
    JOURNAL OF GENE MEDICINE 7/ :39-49,2005
  • RET/PTC and CK19 expression in papillary thyroid carcinoma and its clinicopathologic correlation
    JOURNAL OF KOREAN MEDICAL SCIENCE 20/ :98-104,2005
  • A novel IVS2-1G> A mutation causes aberrant splicing of the HRPT2 gene in a family with hyperparathyroidism-jaw tumor syndrome
    JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 90/2 :878-883,2005
  • High prevalence of c-RET expression in papillary thyroid carcinomas from the Korean population
    THYROID 15/3 :259-266,2005
  • Hemangioblastoma originated from the lumbar soinal nerve root
    korean journal of spine 2/1 :72-74,2005
  • 육아종성 유방염의 임상 및 병리학적 특성
    KOREAN JOURNAL OF PATHOLOGY 39/3 :181-186,2005
  • 갑상샘 세침흡인 세포검사 진단지침과 유두암종의 세포소견에 대한 이해
    대한세포병리학회지(Korean Journal Of Cytopathology) 16/1 :1-9,2005
  • Acute respiratory failure with cervically located benign cystic thyroid mass
    THYROID 15/10 :1197-1198,2005
  • Focal eosinophilic necrosis versus metastasis in the liver: The usefulness of two-phase dynamic CT
    AMERICAN JOURNAL OF ROENTGENOLOGY 184/ :1085-1090,2005
  • Papillary Thyroid Carcinoma Associated with Familial Adenomatous Polyposis: Molecular Analysis of Pathogenesis in a Familyand Review of the Literature
    ENDOCRINE JOURNAL 51/3 :317-323,2005
  • Duodenal somatostatinoma associated with diabetic ketoacidosis presumably caused by somatostatin-28 hypersecretion
    JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 90/ :6310-6315,2005
  • 경부와 종격동에 발생한 캐슬만씨 병(Castleman's Disease)
    대한두경부종양학회지 21/1 :48-52,2005
  • 기도협착을 유발한 흉선낭종
    대한기관식도과학회지 11/1 :25-27,2005
  • 식도 점막하 종양형태로 발현된 이차성 식도 결핵 3예
    대한소화기내시경학회지(Korean J Gastrointest Endosc) 30/2 :80-85,2005
  • Thoracic Mobile schwannoma
    korean journal of spine 2/1 :75-79,2005
  • 갑상선암의 초음파 검진의 유용성 : 유방암군과 비유방암군의 비교
    대한유방검진학회지 2/ :32-35,2005
  • 내경정맥의 암성혈전을 보인 분화 갑상선암종 1예
    대한내분비외과학회지 5/1 :32-35,2005
  • 경부에 발생한 섬유종증 1예
    대한내분비외과학회지 5/1 :36-39,2005
  • 귀밑샘에 발생한 점액 화생을 동반한 만성 경화침샘염의 세침흡인 세포소견 -증례 보고-
    대한세포병리학회지(Korean Journal Of Cytopathology) 16/2 :102-105,2005
  • Induced expression of insulin-like growth factor-1 by amniotic membrane-conditioned medium in cultured human corneal epithelial cells
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 47/ :864-872,2006
  • Topical 0.1% prednisolone lowers nerve growth factor expression in keratoconjunctivitis sicca patients
    OPHTHALMOLOGY 113/ :198-205,2006
  • 점액세포가 관찰되는 침샘 관암종-세침흡인 세포검사에서 점액표피모양암종으로 오인했던 1예 보고-
    대한세포병리학회지(Korean Journal Of Cytopathology) 17/1 :56-62,2006
  • Intraoperative examination of sentinel lymph nodes by immunohistochemical staining in patients with breast cancer
    EUROPEAN JOURNAL OF SURGICAL ONCOLOGY 32/4 :405-409,2006
  • Multinucleation of koilocytes is actually multilobation
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER 16/2 :686-689,2006
  • 갑상선 유두암을 동반한 제1형 다발성 내분비 선종증 1예
    대한내분비학회지(Joornal of the Korean Society of Endocrinol) 21/1 :79-84,2006
  • 양측성 뇌하수체 종양으로 인한 말단비대증 1예
    대한내분비학회지(Joornal of the Korean Society of Endocrinol) 21/1 :53-57,2006
  • 다발성으로 전이된 저등급 자궁내막 간질성 육종 1예
    대한산부인과학회지(KOREAN JOURNAL OF OBSTETRICS AND GYNECOLOLY) 49/9 :1993-1998,2006
  • Sonographic detection of intrathyroidal branchial cleft cyst: A case report
    KOREAN JOURNAL OF RADIOLOGY 7/2 :149-151,2006
  • 이하선 종양으로 오인된 모기질종 2 예
    대한두경부종양학회지 22/2 :147-150,2006
  • 갑상선 미분화암으로 오인된 전이성 폐암
    대한내과학회지(korean Journal of medcine) 71/3 :316-321,2006
  • 가역적인 뇌하수체전엽호르몬의 기능변화를 보인 부신성 쿠싱증후군환자 1예
    대한내분비학회지(Joornal of the Korean Society of Endocrinol) 21/2 :146-152,2006
  • Severe hypothyroidism induced by thyroid metastasis of colon adenocarcinoma: A case report and review of the literature
    ENDOCRINE JOURNAL 53/3 :339-343,2006
  • Ectopic expression of neutrophil gelatinase-associated lipocalin suppresses the invasion and liver metastasis of colon cancer cells
    INTERNATIONAL JOURNAL OF CANCER 118/ :2490-2497,2006
  • Sonographic screening for thyroid cancer in females undergoing breast sonography
    AMERICAN JOURNAL OF ROENTGENOLOGY 186/ :1025-1028,2006
  • Ultrasonographic Characteristics of Subacute Granulomatous Thyroiditis
    대한영상의학회지 7/4 :229-234,2006
  • Suture granuloma mimicking recurrent thyroid carcinoma on ultrasonography
    YONSEI MEDICAL JOURNAL 47/5 :748-751,2006
  • 건성각결막염 환자에서 스테로이드 점안 후 눈물 신경성장인자의 변화
    대한안과학회지 47/11 :1720-1728,2006
  • 잡종견에서 돼지 신장과 폐를 이용한 혈액관류에서 수술 전ㆍ후 혈액의 IgM, IgG와 이식 장기의 IgM, IgG 침착 정도 변화
    대한흉부외과학회지(Korean Journal Of Thoracic And Cardiovascular Surgery) 40/7 :467-472,2007
  • CT나 MR에서 발견된 부신 종양의 진단에서 18F-FDG PET유용성의 재평가
    대한영상의학회지 57/ :357-363,2007
  • Epidural ondansetron is more effective to prevent postoperative pruritus and nausea than intravenous ondansetron in elective cesarean delivery
    ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA 86/6 :683-687,2007
  • Blockade of oxidative stress by vitamin C ameliorates albuminuria and renal sclerosis in experimental diabetic rats
    YONSEI MEDICAL JOURNAL 48/5 :847-855,2007
  • Sonographic detection of thyroid cancer in breast cancer patients
    YONSEI MEDICAL JOURNAL 48/1 :63-68,2007
  • Diffuse sclerosing variant of papillary carcinoma of the thyroid: ultrasound features with histopathological correlation
    CLINICAL RADIOLOGY 62/ :382-386,2007
  • 신 이형성증에서 PAX2 발현
    대한병리학회지 41/ :69-78,2007
  • Spontaneous pneumothorax in metastatic thyroid papillary carcinoma
    JOURNAL OF CLINICAL ONCOLOGY 25/18 :2616-2618,2007
  • Anti-Histone Acetyltransferase Activity from Allspice Extracts Inhibits Androgen Receptor-Dependent Prostate Cancer CellGrowth
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 71/ :70306-70314,2007
  • 소변검사의 재검 시 세포원심분리법과 액상세포검사 ThinPrep?의 효율성에 관한 비교
    대한세포병리학회지(Korean Journal Of Cytopathology) 18/1 :55-61,2007
  • 재발 유두 갑상선암의 부신전이 1예
    대한두경부종양학회지 23/1 :50-53,2007
  • 유두 갑상선암의 왈틴 양 변이의 임상병리적 특성
    대한내분비외과학회지 7/4 :257-259,2007
  • 다발성 점막하종양 형태로 발현된 원발성 직장 MALT 림프종 1예
    대한소화기내시경학회지(Korean J Gastrointest Endosc) 35/ :272-276,2007
  • Androgen-dependent activation of human cytomegalovirus major immediate-early promoter in prostate cancer cells
    Prostate 68/ :1450-1460,2008
  • 측두하악관절에 발생한 염증성 활액낭의 치험례
    대한악안면성형재건외과학회지(J Korean Assoc Maxillofac Plast Reconstr Surg) 30/3 :292-295,2008
  • Papillary thyroid carcinoma with nodular fasciitis-like stroma
    Thyroid 18/ :577-578,2008
  • The role of ultrasound in thyroid nodules with a cytology reading of Suspicious for Papillary Thyroid Carcinoma``
    Thyroid 18/ :517-522,2008
  • 아급성 육아종성 갑상샘염의 세침흡인 세포소견- 아급성 육아종성 갑상샘염 10예의 임상-세포소견 및 면역세포염색 소견 분석
    대한세포병리학회지(Korean Journal Of Cytopathology) 19/1 :27-33,2008
  • Indeterminate Cell Histiocytosis 1예
    대한피부과학회지 46/5 :724-726,2008
  • Anaplastic thyroid carcinoma arising from a calcified thyroid mass
    Journal Of Clinical Oncology 26/ :3800-3802,2008
  • Benign intracystic papilloma of the male breast
    Journal Of Ultrasound In Medicine 29/ :1397-1400,2008
  • 중수골에 발생한 근상피세포종 양상의 종괴 - 증례 보고 -
    대한수부외과학회지(The Journal of the Korean Society for Surgery of the Hand) 13/2 :117-121,2008
  • Sonographic features of the follicular variant of papillary thyroid carcinoma
    Journal Of Ultrasound In Medicine 27/10 :1431-1437,2008
  • Sonographic differentiation of thyroid nodules with eggshell calcifications
    Journal Of Ultrasound In Medicine 27/ :1425-1430,2008
  • Genomic and proteomic characterization of YDOV-157, a newly established human epithelial ovarian cancer cell line
    MOLECULAR AND CELLULAR BIOCHEMISTRY 319/1-2 :189-201,2008
  • Prostate cancer: Added value of subtraction dynamic imaging in 3T magnetic resonance imaging with a phased-array body coil
    Yonsei Medical Journal 49/5 :765-774,2008
  • Adrenocortical oncocytoma displaying intense activity on 18F-FDG-PET: A case report and a literature review
    Annals Of Nuclear Medicine 22/9 :821-824,2008
  • A case of black thyroid associated with hyalinizing trabecular tumor
    Endocrine Journal 55/6 :1109-1112,2008
  • Experimental parathyroid hormone gene therapy using ØC31 integrase
    Endocrine Journal 55/6 :1033-1041,2008
  • 갑상선 결절 진단에서의 초음파유도하 중심부바늘생검의 유용성
    대한초음파의학회지(Journal Of The Korean Society Of Medical Ultrasound) 27/4 :201-211,2008
  • Clinical significance of osteopontin expression in cervical cancer
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 134/ :909-917,2008
  • Interpectoral venous angioma presenting as a breast mass
    Journal Of Ultrasound In Medicine 27/3 :477-481,2008
  • 갑상샘 세침흡인 세포검사와 조직검사의 진단 일치율 및 정확도 분석 -조직학적으로 확진된 322 예에 대한 분석-
    대한세포병리학회지(Korean Journal Of Cytopathology) 19/2 :144-151,2008
  • 갑상선 여포증식성 병변의 세침흡인 세포검사
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  • 폐암 환자의 기관지 세척 검체에 대한 고식적 세포도말검사, 세포 블록, 액상세포검사의 비교
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