바로가기
메인메뉴로 바로가기
콘텐츠 바로가기
하단메뉴로 바로가기
패밀리사이트 바로가기


소속

  • 환경의생물학교실

직위

  • 교수

연구실 위치

  • 의과대학 신관 251호

전화/팩스

  • 02) 2228-1843 /

학력사항

  • 서울대학교 자연과학대학 미생물학과 학사(1985)
    조지아주립대학교 자연과학대학 미생물학과 석사(1989)
    캘리포니아주립대학교 자연과학대학 미생물 및 분자유전학과 박사(1994)

교육 및 연구 경력

  • 1994.-1995. 미국 스탠포드대학교 의과대학 생화학과 (Post.Doc.)
    1996.-1998. 삼성생명과학연구소 선임연구원
    1998.-현재 연세대학교 의과대학 환경의생물학교실 연구조교수

기타 학술 관련 경력

  • 대한기생충학회 평의원
    한국미생물학회 평의원

연구,관심분야

  • 병원성미생물(Pathogenic Microbiology),
    분화(Differentiation),
    항원(Antigen)

논문

  • Han KL, Lee HJ, Shin MH, Shin HJ, Im KI, Park SJ (2004) The involvement of an integrin-like protein and protein kinase C in amoebic adhesion to fibronectin and amoebic cytotoxicity. Parasitol. Res., 94: 53-60.
  • Lee JH, Rho JB, Park KJ, Kim CB, Han YS, Choi SH, Lee KH, Park SJ (2004) Role of Flagellum and Motility in Pathogenesis of Vibrio vulnificus. Infection and Immunity, 72(8): 4905-4910.
  • Park KJ, Kang MJ, Kim SH, Lee HJ, Lim JK, Choi SH, Park SJ, Lee KH (2004) Isolation and characterizationo f rpoS from a pathogenic bacterium Vibrio vulnificus: role of O in survival of exponential-phase cells under oxidative stress. J. Bacteriol., 186(11): 3304-3312.
  • Han KL, Yong TS, Ryu JS, Hwang UW, Park SJ (2004) Identificationo f the hybrid cluster protein, HCP, from amitochondriate eukaryotes and its phylogenetic implications. J. Microbiol. Biotechnol., 14(1): 134-139.
  • Yang HW, Yong TS, Lee JH, Im KI, Park SJ (2002) Characterization of two glyceraldehyde 3-phosphate dehydrogenase genes in Giadia lamblia. Parasitol. Res., 88: 646-650.
  • Yong T, Han K, Yang H, Park S (2002) PCR-RFLP analysis of Giardia intestinalis using a Giardia-specific gene, Glorf-C4. Parasite, 9: 65-70.
  • Yong TS, Yang HW, Im KI, Park SJ (2000) Encystation of Giardia lamblia by high bile and alkaline pH and its ultrastructural changes during encystation. J. Microbiol. Biotechnol., 10(3): 429-433.
  • Han SJ, Lee YC, Gim BS, Ryu GH, Park SJ, Lane WS, Kim YJ (1999) Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation. Molecular and Cellular Biology 19(2):979-988.
  • Park SJ, Yong TS, Chang J, Im Ki, Soh CT (1999) Characterization of YS-27, an axenic Korean strain of Entamoeba histolytica. Korean Jouranl of Parasitology 37(1):59-62.
  • Park SJ, Yong TS, Yang HW, Lee DH, Lee K (1999) Axenic cultivation and characterization of Giardia lamblia isolated from humans in Korea. Korean Jouranl of Parasitology 37(2):121-125.
  • Yong TS, Lee JS, Lee IY, Park SJ, Park GM, Ree HI, Park JW, Hong CS, Park HS (1999) Identification of Chironomus kiiensis allergens, a dominant species of non-biting midges in Korea. Korean Jouranl of Parasitology 37(3):171-179.
  • Yong TS, Park SJ, Lee DH, Yang HJ, Lee J (1999) Identification of IgE-Reacting Clonorchis sinensis antigens. Yonsei Medical Journal 40(2):178-183.
  • Yong TS, Lee JS, Lee JW, Park SJ, Joen SH, Ree HI, Park JW (1999) Identification and purification of IgE-reactive proteins in German cockroach extract. Yonsei Medical Jouranl 40(3):283-289.
  • Park SJ, Yang ES, Kim-Ha J, Kim YJ (1998) Down regulation of extramacrochaetae mRNA by a Drosophila neural RNA binding protein Rbp9 which is homologous to human Hu proteins. Nucleic Acids Research 26(12):2989-2994.
  • Yong TS, Yang HJ, Park SJ, Kim YK, Lee DH, Lee SM (1998) Immunodiagnosis of clonorchiasis using a recombinant antigen. Korean Journal of Parasitology 36(3):183-189.
  • Park SJ, Chao G, Gunsalus RP (1997) Aerobic regulation of the sucABCD genes of Escherichia coli ,which encodes α-ketoglutarate dehydrogenase and succinyl-CoA synthetase: roles of ArcA, Fnr, and the upstream sdhCDAB promoter. Journal of Bacteriology 179(13):4138-4142.
  • Chao G, Shen J, Tseng CP, Park SJ, Gunsalus RP (1997) Aerobic regulation of isocitrate dehydrogenase gene (icd) expression in Escherichia coli by the arcA and fnr gene products. Journal of Bacteriology 179(13):4299-4304.
  • Kasimoglu E, Park S-J, Malek J, Tseng CP, Gunsalus RP (1996) Transcriptional regulation of the proton-translocating ATPase (atpIBEFHAGDC) operon of Escherichia coli: control by cell growth rate. Journal of Bacteriology 178(19):5563-5567.
  • Park S-J, Tseng CP, Gunsalus RP (1995) Regulation of succinate dehydrogenase (sdhCDAB) operon expression in Escherichia coli in response to carbon supply and anaerobiosis: role of ArcA and Fnr. Molecular Microbiology 15(3):473-482.
  • Park S-J, Gunsalus RP (1995) Oxygen, iron, carbon, and superoxide control of the fumarase fumA and fumC genes of Escherichia coli: role of the arcA, fnr, and soxR gene products. Journal of Bacteriology 177(21):6255-6262.
  • Park S-J, Cotter PA, Gunsalus RP (1995) Regulation of malate dehydrogenase (mdh) gene expression in Escherichia coli in response to oxygen, carbon, and heme availability. Journal of Bacteriology 177(22):6652-6656.
  • Gunsalus RP, Park S-J (1994) Aerobic-anaerobic gene regulation in Escherichia coli: control by the ArcAB and Fnr regulons. Research in Microbiology 145(5-6):437-450.
  • Park, S-J (1994) Regulation of tricarboxylic acid cycles genes in Escherchia coli. Ph.D. dissertation. University of California, Los Angeles, USA.
  • Park S-J, McCabe J, Turna J, Gunsalus RP (1994) Regulation of the citrate synthase (gltA) gene of Escherichia coli in response to anaerobiosis and carbon supply: role of the arcA gene product. Journal of Bacteriology 176(16):5086-5092.
  • Lee IW, Livrelli V, Park S-J, Totis PA, Summers AO (1993) In vivo DNA-protein interaction at the divergent mercury resistant (mer) promoters. II. Repressor/activator (MerR)-RNA polymerase interaction with merOP mutants. Journal of Biological Chemistry 268(4):2632-2639.
  • Park S-J, Wireman J, Summers AO (1992) Genetic analysis of the Tn21 mer operator-promoter. Journal of Bacteriology 174(7):2160-2171.
  • Encystation of Giardia lamblia by high bile and alkaline pH and its ultrastructural changes during encystation
    JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 10/3 :429-433,2000
  • Genotyping of Giardia lamblia isolates from humans in China and Korea using ribosomal DNA sequences
    JOURNAL OF PARASITOLOGY 86/4 :887-891,2000
  • Serodiagnosis of amoebiasis using a recombinant protein fragment of the 29 kDa surface antigen of Entamoeba histolytica
    INTERNATIONAL JOURNAL FOR PARASITOLOGY 30/0 :1487-1491,2000
  • Intestinal parasite infections at an institution for the handicapped in Korea
    Korean J Parasitol 38/3 :179-181,2000
  • Identification of a Clonorchis sinensis gene encoding a vitellaria antigenic protein containing repetitive sequences
    Mol Biochem Parasitol 111/0 :213-216,2000
  • Differential gene expression by iron-limitation in Entamoeba histolytica
    Mol Biochem Parasitol 114/0 :257-260,2001
  • Characterization of two glyceraldeyde 3-phosphate dehydrogenase genes in Giardia lamblia
    PARASITOLOGY RESEARCH 88/0 :646-650,2002
  • PCR-RFLP analysis of Giardia lamblia using a Giardia-specific gene, GLORF-C4
    Parasite 9/1 :65-70,2002
  • Isolation of gene induced in Naegleria fowleri during mouse brain passage
    STRATIGRAPHY AND GEOLOGICAL CORRELATION 38/0 :105-111,2002
  • SmcR and cyclic AMP receptor protein coactivate Vibrio vulnificus vvpE encoding elastase through the RpoS-dependent promoter in a synergistic manner
    Journal of Biologicasl Chemistry 278/46 :45072-45081,2003
  • Identification of Vibrio vulnificus lrp and its influence on survival under various stresses
    JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 13/1 :159-163,2003
  • Identification and characterization of the Vibrio vulnificus phosphomannomutase gene.
    JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 13/1 :149-154,2003
  • Identification of an encystation-specific transcription factor, Myb protein in Giardia lamblia
    Molecular & Biochemical Parasitology 128/0 :167-174,2003
  • Analysis of the genes expressed in Clonorchis sinensis adults using the expressed sequence tag approach
    PARASITOLOGY RESEARCH 91/0 :283-289,2003
  • Regulation of fur expression by RpoS and Fur in Vibrio vulnificus
    JOURNAL OF BACTERIOLOGY 185/19 :5891-5896,2003
  • Identification of the hybrid cluster protein, HCP, from amitochondriate eukaryotes and its phylogenetic implications
    JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 14/ :134-139,2004
  • Isolation and characterization of rpoS from a pathogenic bacterium, Vibrio vulnificus: Role of sigma(S) in survival of exponential-phase cells under oxidative stress
    JOURNAL OF BACTERIOLOGY 186/ :3304-3312,2004
  • Role of flagellum and motility in pathogenesis of Vibrio vulnificus
    INFECTION AND IMMUNITY 72/8 :4905-4910,2004
  • The involvement of an integrin-like protein and protein kinase C in amoebic adhesion to fibronectin and amoebic cytotoxicity
    PARASITOLOGY RESEARCH 94/ :53-60,2004
  • Ultrastructural observation of human neutrophils during apoptotic cell death triggered by Entamoeba histolytica (Brief Communication)
    KOREAN JOURNAL OF PARASITOLOGY 42/4 :205-208,2004
  • NADPH oxidase-derived reactive oxygen species-mediated activation of ERK1/2 is required for apoptosis of human neutrophils induced by Entamoeba histolytica
    JOURNAL OF IMMUNOLOGY 174/4 :4279-4288,2005
  • 세균 생물막 형성의 단계별 특징
    JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 33/1 :1-8,2005
  • Interaction of β-Giardin with the Bop1 Protein in Giardia lamblia
    PARASITOLOGY RESEARCH 98/ :138-144,2006
  • Identification of differentially expressed cDNAs in Acanthamoeba culbertsoni after mouse brain passage
    KOREAN JOURNAL OF PARASITOLOGY 44/1 :15-20,2006
  • In vivo determination of the gap2 gene promoter activity in Giardia lamblia
    KOREAN JOURNAL OF PARASITOLOGY 44/1 :21-26,2006
  • Identification of OmpU of vibrio vulnificus as a fibronectin-binding protein and its role in bacterial pathogenesis
    INFECTION AND IMMUNITY 74/ :5586-5594,2006
  • Transcriptional regulatory cascade for elastase production in Vibrio vulnificus: LuxO activates luxT expression and LuxT represses smcR expression
    JOURNAL OF BIOLOGICAL CHEMISTRY 281/46 :34775-34784,2006
  • Hydrogenosomal activity of Trichomonas vaginalis cultivated under different iron conditions
    KOREAN JOURNAL OF PARASITOLOGY 44/4 :373-378,2006
  • Detection and genotyping of Giardia intestinalis isolates using intergenic apacer (IGS)-based PCR
    THE KOREAN JOURNAL OF PARASITOLOGY 44/4 :343-353,2006
  • Involvement of beta2-integrin in ROS-mediated neutrophil
    MICROBES AND INFECTION 9/ :1368-1375,2007
  • Role of NtrC in biofilm formation via controlling expression of the gene encoding an ADP-glycero-manno-heptose-6-epimerase in the pathogenic bacterium, Vibrio vulnificus
    MOLECULAR MICROBIOLOGY 63/2 :559-574,2007
  • Positive regulation of fur gene expression via direct interaction of Fur in a pathogenic bacterium, Vibrio vulnificus
    JOURNAL OF BACTERIOLOGY 189/7 :2629-2636,2007
  • Vibrio vulnificus IlpA-induced cytokine production is mediated by toll-like receptor 2
    JOURNAL OF BIOLOGICAL CHEMISTRY 282/38 :27647-27658,2007
  • Effect of iron on adherence and cytotoxicity of Entamoleba histolytica to CHO cell monolayers
    Korean Journal Of Parasitology 46/ :37-40,2008
  • Identification and characterization of a mitochondrial iron-superoxide dismutase of Cryptosporidium parvum
    Parasitology Research 103/ :787-795,2008
  • Vibrio vulnificus rpoS expression is repressed by direct binding of cAMP-cAMP receptor protein complex to its two promoter regions
    Journal of Biological Chemistry 283/45 :30438-30450,2008
  • Interaction of BOP1, a protein for ribosome biogenesis, with EB1 in Giardia lamblia
    Parasitology Research 103/ :1459-1464,2008
  • Vibrio vulnificus-induced death of Jurkat T-cells requires activation of p38 mitogen-activated protein kinase by NADPH oxidase-derived reactive oxygen species
    Cellular Immunology 253/ :81-91,2008
  • Giardia lamblia EB1 is a functional homolog of yeast Bim1p that binds to microtubules
    Parasitology International 57/ :465-471,2008
  • Comparative proteomic analysis of trophozoites versus cysts of Giardia lamblia
    Parasitology Research 104/ :475-479,2009
  • Vibrio vulnificus-induced Cell Death of Human Mononuclear Cells Requires ROS-dependent Activation of p38 and ERK 1/2 MAPKs
    Immunological Investigations 38/ :31-48,2009
  • Evaluation of alpha-Tubulin as an Antigenic and Molecular Probe to Detect Giardia lamblia
    Korean Journal Of Parasitology 47/3 :287-291,2009
  • Giardia lamblia: Immunogenicity and intracellular distribution of GHSP-115, a member of the Giardia head-stalk family of proteins
    Experimental Parasitology 122/1 :11-16,2009
  • Role of NtrC-regulated exopolysaccharides in the biofilm formation and pathogenic interaction of Vibrio vulnificus
    Molecular Microbiology 74/2 :436-453,2009
  • Expression of the cpdA gene, encoding a 3′,5′-cyclic AMP (cAMP) phosphodiesterase, is positively regulated by the cAMP-cAMP receptor protein complex
    JOURNAL OF BACTERIOLOGY 191/3 :922-930,2009
  • Potential role of HMG coA reductase inhibitor on oxidative stress induced by advanced glycation endproducts in vascular smooth muscle cells of diabetic vasculopathy.
    Experimental And Molecular Medicine 41/11 :802-811,2009
  • Identification of end-binding 1 (EB1) interacting proteins in Giardia lamblia
    Parasitology Research 106/0 :723-728,2010
  • Functional Characterization of the IlpA Protein of Vibrio vulnificus as an Adhesin and Its Role in Bacterial Pathogenesis
    Infection And Immunity 78/6 :2408-2417,2010
  • Prevalence of pediculosis capitis among Korean children
    Parasitology Research 107/6 :1415-1419,2010
  • A mammalian insulysin homolog is regulated by enzyme IIA(Glc) of the glucose transport system in Vibrio vulnificus
    Febs Letters 584/ :4537-4544,2010
  • NF-κB and CREB Are Involved in IL-8 Production of Human Neutrophils Induced by Trichomonas vaginalis-Derived Secretory Products
    KOREAN JOURNAL OF PARASITOLOGY 49/3 :291-294,2011
  • Crystal structure of Toll-like receptor 2-activating lipoprotein IlpA from Vibria vulnificus
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 79/ :1020-1025,2011
  • Complete Genome Sequence of Vibrio vulnificus MO6-24/O
    JOURNAL OF BACTERIOLOGY 193/ :2062-2063,2011
  • Cell Death Mediated by Vibrio parahaemolyticus Type III Secretion System 1 Is Dependent on ERK1/2 MAPK, but Independent of Caspases
    JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 21/9 :903-913,2011
  • Identification of Antigenic Proteins in Trichomonas vaginalis
    KOREAN JOURNAL OF PARASITOLOGY 49/1 :79-83,2011
  • Functional Characterization of EpsC, a Component of the Type II Secretion System, in the Pathogenicity of Vibrio vulnificus
    INFECTION AND IMMUNITY 79/10 :4068-4080,2011
  • Vibrio vulnificus IlpA induces MAPK-mediated cytokine production via TLR1/2 activation in THP-1 cells, a human monocytic cell line
    MOLECULAR IMMUNOLOGY 49/ :143-154,2011
  • FrsA functions as a cofactor-independent decarboxylase to control metabolic flux
    NATURE CHEMICAL BIOLOGY 7/7 :434-436,2011
  • NF-kB and CREB are involved in IL-8 production of human neutrophils induced by Trichomonas vaginalis-derived secretory products
    KOREAN JOURNAL OF PARASITOLOGY 49/3 :291-294,2011
  • Identification of antigenic proteins in Trichomonas vaginalis
    KOREAN JOURNAL OF PARASITOLOGY 49/1 :79-83,2011
  • Excretory-secretory products of Giardia lamblia induce interleukin-8 production in human colonic cells via activation of p38, ERK1/2 NF-kB and AP-1
    PARASITE IMMUNOLOGY 34/4 :183-198,2012
  • Identification of α-11 giardin as a flagellar and surface component of Giardia lamblia
    EXPERIMENTAL PARASITOLOGY 135/2 :227-233,2013
  • Role of capsular polysaccharide(CPS) in biofilm formation and regulation of CPS production by quorum-sensing in Vibrio vulnificus
    MOLECULAR MICROBIOLOGY 90/4 :841-857,2013
  • Regulation of haemolysin(VvhA) production by ferric uptake regulator (Fur) in Vibrio vulnificus: repression of vvhA transcription by Fur and proteolysis of VVhA by Fur-repressive exoproteases
    MOLECULAR MICROBIOLOGY 88/4 :813-826,2013
  • Characterization of microtubule-binding and dimerizatino activity of Giardia lamblia end-binding 1 protein
    PLOS ONE 9/Issue 5 :e97850-,2014
  • Giardia lamblia binding immunoglobulin protein triggers maturation of dendritic cells via activation of TLR4-MyD88-p38 and ERK1/2 MAPKs
    PARASITE IMMUNOLOGY 36/12 :627-646,2014
  • VvpM, an Extracellular Metalloprotease of Vibrio vulnificus, Induces Apoptotic Death of Human Cells
    JOURNAL OF MICROBIOLOGY 52/12 :1036-1043,2014
  • VvpM induces human cell death via multifarious modes including necroptosis and autophagy
    JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 25/2 :302-306,2015
  • Role of VcrD1 protein in expression and secretion of flagellar components in Vibrio parahaemolyticus
    ARCHIVES OF MICROBIOLOGY 197/3 :397-410,2015
  • Role of AcsR in expression of the acetyl-CoA synthetase gene in Vibrio vulnificus
    BMC MICROBIOLOGY 15/86 :1-16,2015
  • Stationary-phase induction of vvpS expression by three transcription factors: repression by LeuO and activation by SmcR and CRP
    MOLECULAR MICROBIOLOGY 97/2 :330-346,2015
  • Comparison between mixed lysate antigen and alpha-actinin antigen in ELISA for serodiagnosis of trichomoniasis
    PARASITOLOGY INTERNATIONAL 64/5 :405-407,2015
  • Identification of a Novel Microtubule-Binding Protein in Giardia lamblia
    KOREAN JOURNAL OF PARASITOLOGY 54/4 :461-469,2016
  • Epigenome mapping highlights chromatin-mediated gene regulation in the protozoan parasite Trichomonas vaginalis
    SCIENTIFIC REPORTS 7/45365 :1-14,2017

박순정

콘텐츠 처음으로 이동

네크워크 링크안내/사이트 정보