바로가기
메인메뉴로 바로가기
콘텐츠 바로가기
하단메뉴로 바로가기
패밀리사이트 바로가기


소속

  • 환경의생물학교실

직위

  • 부교수

연구실 위치

  • 의과대학 신관 251호

전화/팩스

  • 02-2228-1842 /

학력사항

  • 서울대학교 자연과학대학 미생물학과 박사(1998)
    서울대학교 자연과학대학 미생물학과 석사(1992)
    서울대학교 자연과학대학 미생물학과 학사(1990)

기타 학술 관련 경력

  • The International Cytokine Society
    The American Association of Immunologists

연구,관심분야

  • Regulatory T cells and immune tolerance
    cytokines and their receptor
    Epigenetics
    Transcriptional regulation

논문

  • 1. Spolski, R., H. P. Kim, Z. Wu, D. E. Levy, and Warren J. Leonard, 2009. IL-21 mediates suppressive effects via its induction of IL-10. J. Immunol. 182, 2859-67.
  • 2. Kim H. P. and W. J. Leonard, 2007. CREB/ATF-dependent T-cell Receptor-induced Foxp3 Gene Expression: a Role for DNA Methylation. J. Exp. Med. 204, 1543-1551
  • 3. Kim H. P., J. Imbert, and W. J. Leonard, 2006. Both Integrated and Differential Regulation of Components of the IL-2/IL-2 Receptor System. Cytokine & Growth Factor Reviews, 17, 349-366
  • 4. Wu Z., H. P. Kim, H.-H. Xue, H. Liu, K. Zhao, and W. J. Leonard, 2005. IL-21 Receptor Gene Induction in Human T Cells is mediated by TCR-induced Sp1 Expression and Dephosphorylation. Mol. Cel. Biol., 25, 9741-9752
  • 5. Kim H. P., B. G. Kim, J. Letterio, and W. J. Leonard, 2005. Smad-dependent Cooperative Regulation of IL-2 Receptor alpha Chain Gene Expression by TCR and TGF-beta. J. Biol. Chem. 280, 34042-34047.
  • 6. Kim H. P., L. L. Korn, and W. J. Leonard, 2005. Calcium dependent activation of IL-21 gene expression in T cells. J. Biol. Chem. 280, 25291-25297.
  • 7. Ozaki K., R. Spolski, R. Ettinger, H. P. Kim, G. Wang, C.-F. Qi, P. Hwu, D. J. Shaffer, S. Akilesh, D. C. Roopenian, H. C. Morse III, P. E. Lipsky, and Warren J. Leonard, 2004. Regulation of memory B cell development and plasma cell differentiation by IL-21, a novel inducer of Blimp-1 and Bcl-6. J. Immunol. 173, 5361-71.
  • 8. Choi W.S., T. Hiragun, J. H. Lee, Y. M. Kim, H. P. Kim, A. Chahdi, E. Her, J. W. Han, and M. A. Beaven, 2004. Activation of RBL-2H3 Mast Cells Is Dependent on Tyrosine Phosphorylation of Phospholipase D2 by Fyn and Fgr. Mol. Cel. Biol., 24, 6980-6992
  • 9. Kim, H. P., W. J. Leonard, 2002. The Basis for TCR-mediated IL-2 receptor alpha gene regulation: Role of Widely separated regulatory elements. EMBO J., 21, 3051-3059
  • 10. Kim, H. P., J. K. Kelly, and W. J. Leonard, 2001. The basis for IL-2-induced IL-2 receptor alpha chain gene regulation: Importance of two widely separated IL-2 response elements. Immunity, 15, 159-172
  • 11. Kim, H. P., J.-H. Roe, P.Boon Chock, and Moon B. Yim, 1999. Transcriptional activation of the human manganese superoxide dismutase gene mediated by tetradecanoylphobol acetate. J. Biol. Chem., 274, 37455-37460
  • 12. Kim, E.-J., H. P. Kim, Y.-C. Hah, and J.-H Roe, 1996. Differential expression of Ni- and Fe,Zn- containing superoxide dismutases in Streptomyces coelicolor. Eur. J. Biochem., 241, 178-185
  • 13. Kim, H. P., J.-S. Lee, Y.-C. Hah, and J.-H Roe, 1994. Characterization of the majorcatalase from Streptomyces coelicolor ATCC 10147. Microbiology, 140, 3391-3397
  • 14. Kim, H. P., J.-S. Lee, Y.-C. Hah, and J.-H Roe, 1992. Multiple catalases of streptomycescoelicolor. Kor. J. Microbiol. 30, 291-298
  • The basis for IL-2-induced IL-2 receptor a chain gene regulation: Importance of two widely separated IL-2 response elements
    IMMUNITY 15 1:159~172,2001
  • The basis for TCR-mediated regulation of the IL-2 receptor α chain gene: Role of widely separated regulatory elements
    EUROPEAN MOLECULAR BIOLOGY ORGANIZATION JOURNAL 21 12:3051~3059,2002
  • Activation of RBL-2H3 mast cells is dependent on tyrosine phosphorylation of phospholipase D2 by Fyn and Fgr
    MOLECULAR AND CELLULAR BIOLOGY 24 16:6980~6992,2004
  • Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of blimp-1 and bcl-61
    JOURNAL OF IMMUNOLOGY 173 9:5361~5371,2004
  • Calcium-dependent activation of interleukin-21 gene expression in T cells
    JOURNAL OF BIOLOGICAL CHEMISTRY 280 26:25291~25297,2005
  • Smad-dependent cooperative regulation of interleukin 2 receptor alpha chain gene expression by T cell receptor and transforming growth factor-beta
    JOURNAL OF BIOLOGICAL CHEMISTRY 280 40:34042~34047,2005
  • Interleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity
    MOLECULAR AND CELLULAR BIOLOGY 25 22:9741~9752,2005
  • Both integrated and differential regulation of components of the IL-2/IL-2 receptor system
    CYTOKINE & GROWTH FACTOR REVIEWS 17 5:349~366,2006
  • CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: A role for DNA methylation
    JOURNAL OF EXPERIMENTAL MEDICINE 204 7:1543~1551,2007
  • IL-21 mediates suppressive effects via its induction of IL-10.
    Journal Of Immunology 182 5:2859~2867,2009
  • Analysis of Interleukin-21-Induced Prdm1 Gene Regulation Reveals Functional Cooperation of STAT3 and IRF4 Transcription Factors
    Immunity 31 6:941~952,2009
  • DNA methylation-dependent regulation of TrkA, TrkB, and TrkC genes in human hepatocellular carcinoma
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 406 1:89~95,2011
  • Leukotriene B(4) receptor BLT-mediated phosphorylation of NF-κB and CREB is involved in IL-8 production in human mast cells induced by Trichomonas vaginalis-derived secretory products
    MICROBES AND INFECTION 13:1211~1220,2011
  • Accessible chromatin structure permits factors Sp1 and Sp3 to regulate human TGFBI gene expression
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 409 2:222~228,2011
  • Key role for IL-21 in experimental autoimmune uveitis
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108 23:9542~9547,2011
  • Transcriptional activation of the IL31 gene by NFAT and STAT6
    JOURNAL OF LEUKOCYTE BIOLOGY 91 2:245~257,2012
  • High dose bisphenol a impairs hippocampal neurogenesis in female mice across generations
    TOXICOLOGY 296 1-3:73~82,2012
  • IL-21 promotes the pathologic immune response to pneumovirus infection
    JOURNAL OF IMMUNOLOGY 188 4:1924~1932,2012
  • Transcriptional and epigenetic networks in the development and maturation of dendritic cells
    EPIGENOMICS 5 2:195~204,2013
  • Transcription Factors Sp1 and Sp3 Regulated Expression of Human ABCG2 Gene and Chemoresistance Phenotype
    Molecules and Cells 36 4:368~375,2013
  • The pathophysiological role of dendritic cell subsets in psoriasis
    BMB REPORTS 47 2:60~68,2014

김형표

콘텐츠 처음으로 이동

네크워크 링크안내/사이트 정보